diff --git a/DESCRIPTION b/DESCRIPTION
index 8945db0f..30e4c325 100644
--- a/DESCRIPTION
+++ b/DESCRIPTION
@@ -1,6 +1,6 @@
 Package: PhyloProfile
-Version: 1.99.0
-Date: 2024-12-17
+Version: 1.99.1
+Date: 2024-12-20
 Title: PhyloProfile
 Authors@R: c(
     person("Vinh", "Tran", role = c("aut", "cre"), email = "tran@bio.uni-frankfurt.de", comment=c(ORCID="0000-0001-6772-7595")),
diff --git a/inst/PhyloProfile/server.R b/inst/PhyloProfile/server.R
index bb1e9eb4..7e04eca7 100644
--- a/inst/PhyloProfile/server.R
+++ b/inst/PhyloProfile/server.R
@@ -4056,6 +4056,29 @@ shinyServer(function(input, output, session) {
             paste(a, s, b, c, d, e, sep = "\n")
         }
     })
+    
+    # * update highlight gene/taxa by selected point ---------------------------
+    observe({
+        input$highlightMain
+        # GET INFO BASED ON CURRENT TAB
+        if (input$tabs == "Main profile") {
+            shinyjs::enable("highlightMain")
+            # info contains groupID,orthoID,supertaxon,mVar1,%spec,var2
+            info <- isolate(mainpointInfo())
+        } else if (input$tabs == "Customized profile") {
+            shinyjs::disable("highlightMain")
+            info <- NULL
+        }
+        req(info)
+        if (length(info) > 1) {
+            updateSelectizeInput(
+                session, "geneHighlight", selected = info[[1]][1]
+            )
+            updateSelectizeInput(
+                session, "taxonHighlight", selected = info[[4]][1]
+            )
+        }
+    })
 
     # ============================= DETAILED PLOT ==============================
     # * data for detailed plot -------------------------------------------------
diff --git a/inst/PhyloProfile/ui.R b/inst/PhyloProfile/ui.R
index e0da44b0..e879c588 100644
--- a/inst/PhyloProfile/ui.R
+++ b/inst/PhyloProfile/ui.R
@@ -2461,6 +2461,12 @@ shinyUI(
                         "Domain plot",
                         style = "success",
                         disabled = TRUE
+                    ),
+                    shinyBS::bsButton(
+                        "highlightMain",
+                        "Highlight",
+                        style = "success",
+                        disabled = FALSE
                     )
                 ),
                 style = "opacity: 0.80"