diff --git a/analyzer/codechecker_analyzer/analyzers/config_handler.py b/analyzer/codechecker_analyzer/analyzers/config_handler.py
index bfc8be40fa..e701bd96af 100644
--- a/analyzer/codechecker_analyzer/analyzers/config_handler.py
+++ b/analyzer/codechecker_analyzer/analyzers/config_handler.py
@@ -12,8 +12,10 @@
 
 from abc import ABCMeta
 from enum import Enum
+from string import Template
 import collections
 import platform
+import sys
 import re
 
 from codechecker_analyzer import analyzer_context
@@ -149,10 +151,12 @@ def initialize_checkers(self,
           and "debug" checker groups. "osx" checker group is also not included
           unless the target platform is Darwin.
         - Command line "--enable/--disable" flags.
-          - Their arguments may start with "profile:" or "guideline:" prefix
-            which makes the choice explicit.
-          - Without prefix it means a profile name, a guideline name or a
-            checker group/name in this priority order.
+          - Their arguments may start with "prefix:", "profile:" or
+            "guideline:" label which makes the choice explicit.
+          - Without a label, it means either a profile name, a guideline name
+            or a checker prefix group/name, unless there is a clash
+            between these names, in which case an error is emitted.
+            If there is a name clash, using a label is mandatory.
 
         checkers -- [(checker name, description), ...] Checkers to add with
                     their description.
@@ -210,23 +214,41 @@ def initialize_checkers(self,
         profiles = checker_labels.get_description('profile')
         guidelines = checker_labels.occurring_values('guideline')
 
+        templ = Template("The ${entity} name '${identifier}' conflicts with a "
+                         "checker name prefix '${identifier}'. Please use -e "
+                         "${entity}:${identifier} to enable checkers of the "
+                         "${identifier} ${entity} or use -e "
+                         "prefix:${identifier} to select checkers which have "
+                         "a name starting with '${identifier}'.")
+
         for identifier, enabled in cmdline_enable:
-            if ':' in identifier:
+            if "prefix:" in identifier:
+                identifier = identifier.replace("prefix:", "")
+                self.set_checker_enabled(identifier, enabled)
+
+            elif ':' in identifier:
                 for checker in checker_labels.checkers_by_labels([identifier]):
                     self.set_checker_enabled(checker, enabled)
+
             elif identifier in profiles:
                 if identifier in reserved_names:
-                    LOG.warning("Profile name '%s' conflicts with a "
-                                "checker(-group) name.", identifier)
-                for checker in checker_labels.checkers_by_labels(
-                        [f'profile:{identifier}']):
-                    self.set_checker_enabled(checker, enabled)
+                    LOG.error(templ.substitute(entity="profile",
+                                               identifier=identifier))
+                    sys.exit(1)
+                else:
+                    for checker in checker_labels.checkers_by_labels(
+                            [f'profile:{identifier}']):
+                        self.set_checker_enabled(checker, enabled)
+
             elif identifier in guidelines:
                 if identifier in reserved_names:
-                    LOG.warning("Guideline name '%s' conflicts with a "
-                                "checker(-group) name.", identifier)
-                for checker in checker_labels.checkers_by_labels(
-                        [f'guideline:{identifier}']):
-                    self.set_checker_enabled(checker, enabled)
+                    LOG.error(templ.substitute(entity="guideline",
+                                               identifier=identifier))
+                    sys.exit(1)
+                else:
+                    for checker in checker_labels.checkers_by_labels(
+                            [f'guideline:{identifier}']):
+                        self.set_checker_enabled(checker, enabled)
+
             else:
                 self.set_checker_enabled(identifier, enabled)
diff --git a/analyzer/codechecker_analyzer/checkers.py b/analyzer/codechecker_analyzer/checkers.py
index 1e9b6f7461..23f0c401c3 100644
--- a/analyzer/codechecker_analyzer/checkers.py
+++ b/analyzer/codechecker_analyzer/checkers.py
@@ -23,7 +23,8 @@ def available(ordered_checkers, available_checkers):
         if checker_name.startswith('profile:') or \
                 checker_name.startswith('guideline:') or \
                 checker_name.startswith('severity:') or \
-                checker_name.startswith('sei-cert:'):
+                checker_name.startswith('sei-cert:') or \
+                checker_name.startswith('prefix:'):
             continue
 
         name_match = False
diff --git a/analyzer/codechecker_analyzer/cmd/analyze.py b/analyzer/codechecker_analyzer/cmd/analyze.py
index 42e9336ad4..440018e243 100644
--- a/analyzer/codechecker_analyzer/cmd/analyze.py
+++ b/analyzer/codechecker_analyzer/cmd/analyze.py
@@ -699,6 +699,22 @@ def add_arguments_to_parser(parser):
 Note that compiler errors and warnings are captured by CodeChecker only if it
 was emitted by clang-tidy.
 
+Checker prefix groups
+------------------------------------------------
+Checker prefix groups allow you to enable checkers that share a common
+prefix in their names. Checkers within a prefix group will have names that
+start with the same identifier, making it easier to manage and reference
+related checkers.
+
+You can enable/disable checkers belonging to a checker prefix group:
+'-e <label>:<value>', e.g. '-e prefix:security'.
+
+Note: The 'prefix' label is mandatory when there is ambiguity between the
+name of a checker prefix group and a checker profile or a guideline. This
+prevents conflicts and ensures the correct checkers are applied.
+
+See "CodeChecker checkers --help" to learn more.
+
 Checker labels
 ------------------------------------------------
 Each checker is assigned several '<label>:<value>' pairs. For instance,
@@ -708,6 +724,10 @@ def add_arguments_to_parser(parser):
 You can enable/disable checkers belonging to a label: '-e <label>:<value>',
 e.g. '-e profile:default'.
 
+Note: The 'profile' label is mandatory when there is ambiguity between the
+name of a checker profile and a checker prefix group or a guideline. This
+prevents conflicts and ensures the correct checkers are applied.
+
 See "CodeChecker checkers --help" to learn more.
 
 Guidelines
@@ -723,6 +743,10 @@ def add_arguments_to_parser(parser):
 Guidelines are labels themselves, and can be used as a label:
 '-e guideline:<value>', e.g. '-e guideline:sei-cert'.
 
+Note: The 'guideline' label is mandatory when there is ambiguity between the
+name of a guideline and a checker prefix group or a checker profile. This
+prevents conflicts and ensures the correct checkers are applied.
+
 Batch enabling/disabling checkers
 ------------------------------------------------
 You can fine-tune which checkers to use in the analysis by setting the enable
@@ -739,35 +763,37 @@ def add_arguments_to_parser(parser):
                                metavar='checker/group/profile',
                                default=argparse.SUPPRESS,
                                action=OrderedCheckersAction,
-                               help="Set a checker (or checker group), "
-                                    "profile or guideline "
-                                    "to BE USED in the analysis. In case of "
-                                    "ambiguity the priority order is profile, "
-                                    "guideline, checker name (e.g. security "
-                                    "means the profile, not the checker "
-                                    "group). Moreover, labels can also be "
+                               help="Set a checker (or checker prefix group), "
+                                    "profile or guideline to BE USED in the "
+                                    "analysis. Labels can also be "
                                     "used for selecting checkers, for example "
                                     "profile:extreme or severity:STYLE. See "
                                     "'CodeChecker checkers --label' for "
-                                    "further details.")
+                                    "further details. In case of a name clash "
+                                    "between the checker prefix "
+                                    "group/profile/guideline name, the use of "
+                                    "one of the following labels is "
+                                    "mandatory: 'prefix:', 'profile:', "
+                                    "'guideline:'.")
 
     checkers_opts.add_argument('-d', '--disable',
                                dest="disable",
                                metavar='checker/group/profile',
                                default=argparse.SUPPRESS,
                                action=OrderedCheckersAction,
-                               help="Set a checker (or checker group), "
+                               help="Set a checker (or checker prefix group), "
                                     "profile or guideline "
                                     "to BE PROHIBITED from use in the "
-                                    "analysis. In case of "
-                                    "ambiguity the priority order is profile, "
-                                    "guideline, checker name (e.g. security "
-                                    "means the profile, not the checker "
-                                    "group). Moreover, labels can also be "
+                                    "analysis. Labels can also be "
                                     "used for selecting checkers, for example "
                                     "profile:extreme or severity:STYLE. See "
                                     "'CodeChecker checkers --label' for "
-                                    "further details.")
+                                    "further details. In case of a name clash "
+                                    "between the checker prefix "
+                                    "group/profile/guideline name, the use of "
+                                    "one of the following labels is "
+                                    "mandatory: 'prefix:', 'profile:', "
+                                    "'guideline:'.")
 
     checkers_opts.add_argument('--enable-all',
                                dest="enable_all",
diff --git a/analyzer/codechecker_analyzer/cmd/check.py b/analyzer/codechecker_analyzer/cmd/check.py
index 871d1c6e1d..fa2ef4e505 100644
--- a/analyzer/codechecker_analyzer/cmd/check.py
+++ b/analyzer/codechecker_analyzer/cmd/check.py
@@ -643,6 +643,22 @@ def add_arguments_to_parser(parser):
 Note that compiler errors and warnings are captured by CodeChecker only if it
 was emitted by clang-tidy.
 
+Checker prefix groups
+------------------------------------------------
+Checker prefix groups allow you to enable checkers that share a common
+prefix in their names. Checkers within a prefix group will have names that
+start with the same identifier, making it easier to manage and reference
+related checkers.
+
+You can enable/disable checkers belonging to a checker prefix group:
+'-e <label>:<value>', e.g. '-e prefix:security'.
+
+Note: The 'prefix' label is mandatory when there is ambiguity between the
+name of a checker prefix group and a checker profile or a guideline. This
+prevents conflicts and ensures the correct checkers are applied.
+
+See "CodeChecker checkers --help" to learn more.
+
 Checker labels
 ------------------------------------------------
 Each checker is assigned several '<label>:<value>' pairs. For instance,
@@ -652,6 +668,10 @@ def add_arguments_to_parser(parser):
 You can enable/disable checkers belonging to a label: '-e <label>:<value>',
 e.g. '-e profile:default'.
 
+Note: The 'profile' label is mandatory when there is ambiguity between the
+name of a checker profile and a checker prefix group or a guideline. This
+prevents conflicts and ensures the correct checkers are applied.
+
 See "CodeChecker checkers --help" to learn more.
 
 Guidelines
@@ -667,6 +687,10 @@ def add_arguments_to_parser(parser):
 Guidelines are labels themselves, and can be used as a label:
 '-e guideline:<value>', e.g. '-e guideline:sei-cert'.
 
+Note: The 'guideline' label is mandatory when there is ambiguity between the
+name of a guideline and a checker prefix group or a checker profile. This
+prevents conflicts and ensures the correct checkers are applied.
+
 Batch enabling/disabling checkers
 ------------------------------------------------
 You can fine-tune which checkers to use in the analysis by setting the enable
diff --git a/analyzer/tests/unit/test_checker_handling.py b/analyzer/tests/unit/test_checker_handling.py
index 7c5dd81db4..81e36f09ef 100644
--- a/analyzer/tests/unit/test_checker_handling.py
+++ b/analyzer/tests/unit/test_checker_handling.py
@@ -39,9 +39,17 @@ def checkers_by_labels(self, labels):
         if labels[0] == 'profile:default':
             return ['core', 'deadcode', 'security.FloatLoopCounter']
 
+        if labels[0] == 'prefix:security':
+            return ['security.insecureAPI.bzero',
+                    'security.insecureAPI.getpw']
+
         if labels[0] == 'profile:security':
             return ['alpha.security']
 
+        if labels[0] == 'profile:sensitive':
+            return ['alpha.core.BoolAssignment',
+                    'alpha.core.TestAfterDivZero']
+
         if labels[0] == 'guideline:sei-cert':
             return ['alpha.core.CastSize', 'alpha.core.CastToStruct']
 
@@ -154,6 +162,17 @@ def f(checks, checkers):
                 'alpha.security.ArrayBound',
                 'alpha.security.MallocOverflow']
 
+        # "security" checker prefix group
+        security_prefix = [
+            'security.insecureAPI.bzero',
+            'security.insecureAPI.getpw'
+        ]
+
+        # "sensitive" profile, but alpha -> not in default.
+        sensitive_profile_alpha = [
+                    'alpha.core.BoolAssignment',
+                    'alpha.core.TestAfterDivZero']
+
         # "default" profile.
         default_profile = [
                 'security.FloatLoopCounter',
@@ -175,6 +194,8 @@ def f(checks, checkers):
 
         checkers = []
         checkers.extend(map(add_description, security_profile_alpha))
+        checkers.extend(map(add_description, security_prefix))
+        checkers.extend(map(add_description, sensitive_profile_alpha))
         checkers.extend(map(add_description, default_profile))
         checkers.extend(map(add_description, cert_guideline))
         checkers.extend(map(add_description, statisticsbased))
@@ -197,15 +218,41 @@ def f(checks, checkers):
         self.assertTrue(all_with_status(CheckerState.ENABLED)
                         (cfg_handler.checks(), default_profile))
 
+        # Enable alpha checkers explicitly with prefix label.
+        # Using the "prefix" label is optional in this case, because the
+        # checker group name "alpha" does not conflict with any checker
+        # profiles or guidelines.
+        cfg_handler = ClangSA.construct_config_handler(args)
+        cfg_handler.initialize_checkers(checkers,
+                                        [('prefix:alpha', True)])
+        self.assertTrue(all_with_status(CheckerState.ENABLED)
+                        (cfg_handler.checks(), security_profile_alpha))
+        self.assertTrue(all_with_status(CheckerState.ENABLED)
+                        (cfg_handler.checks(), default_profile))
+
         # Enable alpha checkers explicitly.
         cfg_handler = ClangSA.construct_config_handler(args)
-        cfg_handler.initialize_checkers(checkers, [('alpha', True)])
+        cfg_handler.initialize_checkers(checkers,
+                                        [('alpha', True)])
         self.assertTrue(all_with_status(CheckerState.ENABLED)
                         (cfg_handler.checks(), security_profile_alpha))
         self.assertTrue(all_with_status(CheckerState.ENABLED)
                         (cfg_handler.checks(), default_profile))
 
+        # Enable checkers of the "security" checker prefix group.
+        # Using the "prefix" label is mandatory in this case, because the
+        # checker group name "security" conflicts with a profile name.
+        cfg_handler = ClangSA.construct_config_handler(args)
+        cfg_handler.initialize_checkers(checkers,
+                                        [('prefix:security', True)])
+        self.assertTrue(all_with_status(CheckerState.ENABLED)
+                        (cfg_handler.checks(), security_prefix))
+        self.assertTrue(all_with_status(CheckerState.ENABLED)
+                        (cfg_handler.checks(), default_profile))
+
         # Enable "security" profile checkers.
+        # Using the "profile" label is mandatory in this case, because the
+        # profile name "security" conflicts with a checker group name.
         cfg_handler = ClangSA.construct_config_handler(args)
         cfg_handler.initialize_checkers(checkers,
                                         [('profile:security', True)])
@@ -215,22 +262,46 @@ def f(checks, checkers):
                         (cfg_handler.checks(), default_profile))
 
         # Enable "security" profile checkers without "profile:" prefix.
+        # This should throw an error, because the profile name "security"
+        # conflicts with a checker group name.
+        cfg_handler = ClangSA.construct_config_handler(args)
+        with self.assertRaises(SystemExit) as e:
+            cfg_handler.initialize_checkers(checkers,
+                                            [('security', True)])
+        self.assertEqual(e.exception.code, 1)
+
+        # Enable "sensitive" profile checkers with the "profile:" label.
+        # Using the "profile" label is optional in this case, because the
+        # profile name "sensitive" does not conflict with any checker
+        # prefix group names.
         cfg_handler = ClangSA.construct_config_handler(args)
         cfg_handler.initialize_checkers(checkers,
-                                        [('security', True)])
+                                        [('profile:sensitive', True)])
         self.assertTrue(all_with_status(CheckerState.ENABLED)
-                        (cfg_handler.checks(), security_profile_alpha))
+                        (cfg_handler.checks(), sensitive_profile_alpha))
+        self.assertTrue(all_with_status(CheckerState.ENABLED)
+                        (cfg_handler.checks(), default_profile))
+
+        # Enable "sensitive" profile checkers without the "profile:" label.
+        cfg_handler = ClangSA.construct_config_handler(args)
+        cfg_handler.initialize_checkers(checkers,
+                                        [('sensitive', True)])
+        self.assertTrue(all_with_status(CheckerState.ENABLED)
+                        (cfg_handler.checks(), sensitive_profile_alpha))
         self.assertTrue(all_with_status(CheckerState.ENABLED)
                         (cfg_handler.checks(), default_profile))
 
-        # Enable "sei-cert" guideline checkers.
+        # Enable "sei-cert" guideline checkers with the "guideline:" label.
+        # Using the "guideline" label is optional in this case, because the
+        # guideline name "sei-cert" does not conflict with any checker
+        # prefix group names.
         cfg_handler = ClangSA.construct_config_handler(args)
         cfg_handler.initialize_checkers(checkers,
                                         [('guideline:sei-cert', True)])
         self.assertTrue(all_with_status(CheckerState.ENABLED)
                         (cfg_handler.checks(), cert_guideline))
 
-        # Enable "sei-cert" guideline checkers.
+        # Enable "sei-cert" guideline checkers without the "guideline:" label.
         cfg_handler = ClangSA.construct_config_handler(args)
         cfg_handler.initialize_checkers(checkers,
                                         [('sei-cert', True)])
diff --git a/docs/analyzer/user_guide.md b/docs/analyzer/user_guide.md
index e8bba6ad95..55b07a4ed7 100644
--- a/docs/analyzer/user_guide.md
+++ b/docs/analyzer/user_guide.md
@@ -389,6 +389,22 @@ checker configuration:
   Note that compiler errors and warnings are captured by CodeChecker only if it
   was emitted by clang-tidy.
 
+  Checker prefix groups
+  ------------------------------------------------
+  Checker prefix groups allow you to enable checkers that share a common 
+  prefix in their names. Checkers within a prefix group will have names that 
+  start with the same identifier, making it easier to manage and reference 
+  related checkers.
+  
+  You can enable/disable checkers belonging to a checker prefix group: 
+  '-e <label>:<value>', e.g. '-e prefix:security'.
+  
+  Note: The 'prefix' label is mandatory when there is ambiguity between the
+  name of a checker prefix group and a checker profile or a guideline. This 
+  prevents conflicts and ensures the correct checkers are applied.
+  
+  See "CodeChecker checkers --help" to learn more.
+
   Checker labels
   ------------------------------------------------
   Each checker is assigned several '<label>:<value>' pairs. For instance,
@@ -397,6 +413,10 @@ checker configuration:
 
   You can enable/disable checkers belonging to a label: '-e <label>:<value>',
   e.g. '-e profile:default'.
+  
+  Note: The 'profile' label is mandatory when there is ambiguity between the
+  name of a checker profile and a checker prefix group or a guideline. This 
+  prevents conflicts and ensures the correct checkers are applied.
 
   See "CodeChecker checkers --help" to learn more.
 
@@ -412,6 +432,10 @@ checker configuration:
 
   Guidelines are labels themselves, and can be used as a label:
   '-e guideline:<value>', e.g. '-e guideline:sei-cert'.
+  
+  Note: The 'guideline' label is mandatory when there is ambiguity between the
+  name of a guideline and a checker prefix group or a checker profile. This 
+  prevents conflicts and ensures the correct checkers are applied.
 
   Batch enabling/disabling checkers
   ------------------------------------------------