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DESCRIPTION
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Package: SNPRelate
Type: Package
Title: Parallel Computing Toolset for Relatedness and Principal Component
Analysis of SNP Data
Version: 1.1.11
Date: 2015-03-26
Depends: R (>= 2.14), gdsfmt (>= 1.2.2)
LinkingTo: gdsfmt
Suggests: parallel, RUnit, knitr, MASS, BiocGenerics
Authors@R: c(person("Xiuwen", "Zheng", role=c("aut", "cre", "cph"),
email="[email protected]"),
person("Stephanie", "Gogarten", role="ctb"),
person("Cathy", "Laurie", role="ctb"),
person("Bruce", "Weir", role=c("ctb", "ths"),
email="[email protected]"))
Description: Genome-wide association studies (GWAS) are widely used to
investigate the genetic basis of diseases and traits, but they
pose many computational challenges. We developed an R package
SNPRelate to provide a binary format for single-nucleotide
polymorphism (SNP) data in GWAS utilizing CoreArray Genomic
Data Structure (GDS) data files. The GDS format offers the
efficient operations specifically designed for integers with
two bits, since a SNP could occupy only two bits. SNPRelate is
also designed to accelerate two key computations on SNP data
using parallel computing for multi-core symmetric
multiprocessing computer architectures: Principal Component
Analysis (PCA) and relatedness analysis using
Identity-By-Descent measures. The SNP format in this package is
also used by the GWASTools package with the support of S4
classes and generic functions.
License: GPL-3
VignetteBuilder: knitr
URL: http://github.com/zhengxwen/SNPRelate,
http://corearray.sourceforge.net/tutorials/SNPRelate/
BugReports: http://github.com/zhengxwen/SNPRelate/issues
biocViews: Infrastructure, Genetics, StatisticalMethod, PrincipalComponent