DESCRIPTION

Package: surrosurv
Type: Package
Title: Evaluation of Failure Time Surrogate Endpoints in Individual Patient Data
    Meta-Analyses
Version: 1.1.25
Date: 2017-12-13
Authors@R: c(
  person("Federico", "Rotolo", email="federico.rotolo@gustaveroussy.fr", 
          role=c("aut", "cre")),
  person("Xavier", "Paoletti", role="ctr"),
  person("Marc", "Buyse", role="ctr"),
  person("Tomasz", "Burzykowski", role="ctr"),
  person("Stefan", "Michiels", role="ctr"))
Author: Federico Rotolo [aut, cre],
  Xavier Paoletti [ctr], Marc Buyse [ctr], Tomasz Burzykowski [ctr], Stefan Michiels [ctr]
Maintainer: Federico Rotolo <federico.rotolo@gustaveroussy.fr>
Description: Provides functions for the evaluation of
    surrogate endpoints when both the surrogate and the true endpoint are failure
    time variables. The approaches implemented are:
    (1) the two-step approach (Burzykowski et al, 2001) <DOI:10.1111/1467-9876.00244> with a copula model (Clayton, Plackett, Hougaard) at
    the first step and either a linear regression of log-hazard ratios at the second
    step (either adjusted or not for measurement error);
    (2) mixed proportional hazard models estimated via mixed Poisson GLM
    (Rotolo et al, 2017 <DOI:10.1177/0962280217718582>).
Depends: R (>= 2.10), stats, optimx, grDevices
Imports:
    copula,
    eha,
    lme4,
    MASS,
    Matrix, 
    msm,
    mvmeta,
    optextras,
    parallel,
    parfm,
    survival,
    SurvCorr
License: GPL-2
VignetteBuilder: R.rsp
Suggests: R.rsp
Encoding: UTF-8