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NEWS.md

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assemblerr 0.1.2

  • regenerate help files for compatability with new CRAN check

assemblerr 0.1.1

  • add CWRES to vars_nm_std
  • pk_elimination_linear_nl gains support for CLmm and Vmax parameterization

assemblerr 0.1.0

  • First release

assemblerr 0.0.0.9009

  • automatically rename variables with conflicting capitalization (e.g., emax and EMAX)
  • rename pk_elimination_linear_mm() to pk_elimination_linear_nl()
  • remove pk_elimination_mm()
  • extended help for PK component building blocks

assemblerr 0.0.0.9008

  • extended help for the building blocks: parameter, observation, compartment, flow
  • added pkgdown reference
  • added new "Getting started" vignette

assemblerr 0.0.0.9007

  • added task option to render function allowing to customize estimation and covariance records, e.g., render(m, tasks = tsk_estimation(method = "foce"))
  • added tsk_ouput() to specify variables that should be added to $TABLE

assemblerr 0.0.0.9006

  • RUV variance can be specified in the observation model obs_additive(~conc, var_add = 2)
  • default parameter values for PK components
  • parameter values can be defined when specifying parameters prm_normal("k", mean = 1, var = 1)
  • variables that are not defined in the model are automatically added as input variables
  • added warning when a new building block replaces an existing one

assemblerr 0.0.0.9005

  • added pk_elimination_linear_mm for mixed linear-mm elimination
  • models are now checked for issues before rendering
  • improved console printing of building blocks and models

assemblerr 0.0.0.9004

  • added check() function to check and list model issues
  • improved error checking and reporting when creating building blocks, e.g., prm_normal()
  • prediction declarations for observations do not longer need a left-hand side, e.g., obs_additive(~C["central"]) is now valid.
  • pk_elimination_mm has been replaced with pk_elimination_nl to clarify that the default parameterization is not the classical MM model. Additionally, pk_elimination_nl allows selecting the classical parameterization using pk_elimination_nl(prm_vmax = prm_log_normal("vmax"), prm_clmm = NULL)
  • unsupported building blocks are now ignored with a warning when added to a model (e.g., pk_model()+compartment('central'))
  • option to include estimation & covariance step records in generated NONMEM model through render(m, options = assemblerr_options(default_record.covariance_step = nm_covariance()))
  • Added a NEWS.md file to track changes to the package.