DESCRIPTION

Package: wnl
Version: 0.6.3
Title: Minimization Tool for Pharmacokinetic-Pharmacodynamic Data
        Analysis
Description: This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model. 
Depends: R (>= 3.0.0), numDeriv
Author: Kyun-Seop Bae [aut]
Maintainer: Kyun-Seop Bae <k@acr.kr>
Copyright: 2017-, Kyun-Seop Bae
License: GPL-3
NeedsCompilation: no
LazyLoad: yes
Repository: CRAN
URL: https://cran.r-project.org/package=wnl
Packaged: 2021-08-10 03:02:20 UTC; Kyun-SeopBae
Date/Publication: 2021-09-06 04:30:02 UTC
Authors@R: person('Kyun-Seop', 'Bae', email = 'k@acr.kr', role = c('aut'))