From 8c6071b25f29c980096101245077c9faf2b89d8b Mon Sep 17 00:00:00 2001 From: Alec Wysoker Date: Tue, 22 Oct 2024 17:26:23 -0400 Subject: [PATCH 1/2] Fix MANIFEST doc --- .../dropseqrna/barnyard/digitalexpression/MakeTripletDge.java | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/src/java/org/broadinstitute/dropseqrna/barnyard/digitalexpression/MakeTripletDge.java b/src/java/org/broadinstitute/dropseqrna/barnyard/digitalexpression/MakeTripletDge.java index a4785bc8..b7c9fb3a 100644 --- a/src/java/org/broadinstitute/dropseqrna/barnyard/digitalexpression/MakeTripletDge.java +++ b/src/java/org/broadinstitute/dropseqrna/barnyard/digitalexpression/MakeTripletDge.java @@ -70,7 +70,7 @@ public class MakeTripletDge extends AbstractTripletDgeWriterClp { @Argument(shortName = "M", doc= """ yaml input file containing list of DGEs to be merged. - The file is expected to contain a 'datasets' list. Each element of the list will contain: + The file is expected to contain a 'dges' list. Each element of the list will contain: dge: the location of the tabular DGE, which must be lexically sorted by gene. (required) prefix: a prefix to prepend to each CBC. (default: no prefix) From 24fd2d037cef234970046cd93a5049af94473708 Mon Sep 17 00:00:00 2001 From: Alec Wysoker Date: Tue, 22 Oct 2024 18:44:55 -0400 Subject: [PATCH 2/2] Script to concatenate TSVs --- src/python/dropseq_aggregation/pyproject.toml | 1 + .../src/dropseq_aggregation/cat_tsvs.py | 63 +++++++++++ .../tests/test_cat_tsvs.py | 69 ++++++++++++ .../rxn1.joined_filtered_cell_metadata.tsv | 100 ++++++++++++++++++ .../rxn2.joined_filtered_cell_metadata.tsv | 100 ++++++++++++++++++ 5 files changed, 333 insertions(+) create mode 100644 src/python/dropseq_aggregation/src/dropseq_aggregation/cat_tsvs.py create mode 100644 src/python/dropseq_aggregation/tests/test_cat_tsvs.py create mode 100644 testdata/python/dropseq_aggregation/cat_tsvs/rxn1.joined_filtered_cell_metadata.tsv create mode 100644 testdata/python/dropseq_aggregation/cat_tsvs/rxn2.joined_filtered_cell_metadata.tsv diff --git a/src/python/dropseq_aggregation/pyproject.toml b/src/python/dropseq_aggregation/pyproject.toml index 25ec3daf..84837a69 100644 --- a/src/python/dropseq_aggregation/pyproject.toml +++ b/src/python/dropseq_aggregation/pyproject.toml @@ -25,3 +25,4 @@ Issues = "https://github.com/broadinstitute/Drop-seq/issues" [project.scripts] join_and_filter_tsv = "dropseq_aggregation.join_and_filter_tsv:main" +cat_tsvs = "dropseq_aggregation.cat_tsvs:main" diff --git a/src/python/dropseq_aggregation/src/dropseq_aggregation/cat_tsvs.py b/src/python/dropseq_aggregation/src/dropseq_aggregation/cat_tsvs.py new file mode 100644 index 00000000..9b0b64be --- /dev/null +++ b/src/python/dropseq_aggregation/src/dropseq_aggregation/cat_tsvs.py @@ -0,0 +1,63 @@ +#!/usr/bin/env python3 +# MIT License +# +# Copyright 2024 Broad Institute +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in all +# copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE +# SOFTWARE. +"""Read one or more tab-separated files with header, and write a single tab-separated file with rows concatentated from the +input files. The output columns will be the union of all the input columns, with empty values for input files that +lack a column. """ + +import argparse +import sys +import pandas as pd + +from . import logger, add_log_argument + +def main(args=None): + parser = argparse.ArgumentParser(description=__doc__) + add_log_argument(parser) + parser.add_argument("--index-col", "-i", default=None, action="append", + help="Column to use as index. May be specified more than once. If indices are not unique, " + "an error will be raised.") + parser.add_argument("--output", "-o", default=sys.stdout, type=argparse.FileType('w'), + help="Output file. Default: stdout.") + parser.add_argument("input", nargs="+", type=argparse.FileType('r'), + help="Input tab-separated files. May be specified more than once.") + options = parser.parse_args(args) + return run(options) + +def run(options): + dfs = [pd.read_csv(f, sep="\t") for f in options.input] + map(lambda f: f.close(), options.input) + df = pd.concat(dfs) + if options.index_col: + # Check for duplicate keys + duplicate_keys = df[df.duplicated(subset=options.index_col, keep=False)] + + if not duplicate_keys.empty: + logger.error(f"Duplicate keys found: {duplicate_keys[options.index_col]}") + return 1 + + df.to_csv(options.output, sep="\t", index=False) + options.output.close() + return 0 + +if __name__ == "__main__": + sys.exit(main()) diff --git a/src/python/dropseq_aggregation/tests/test_cat_tsvs.py b/src/python/dropseq_aggregation/tests/test_cat_tsvs.py new file mode 100644 index 00000000..66e99fdf --- /dev/null +++ b/src/python/dropseq_aggregation/tests/test_cat_tsvs.py @@ -0,0 +1,69 @@ +#!/usr/bin/env python3 +# MIT License +# +# Copyright 2024 Broad Institute +# +# Permission is hereby granted, free of charge, to any person obtaining a copy +# of this software and associated documentation files (the "Software"), to deal +# in the Software without restriction, including without limitation the rights +# to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +# copies of the Software, and to permit persons to whom the Software is +# furnished to do so, subject to the following conditions: +# +# The above copyright notice and this permission notice shall be included in all +# copies or substantial portions of the Software. +# +# THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +# IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +# FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +# AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +# LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +# OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE +# SOFTWARE. +import collections +import os +import shutil +import tempfile +import unittest +import pandas as pd +import dropseq_aggregation.cat_tsvs + +OptionsTuple = collections.namedtuple("OptionsTuple", ["output", "input", "index_col"], + defaults=[None, None]) + +class TestCatTsvs(unittest.TestCase): + def setUp(self): + self.testDataDir = "../../../testdata/python/dropseq_aggregation/cat_tsvs" + self.tmpDir = tempfile.mkdtemp(".tmp", "cat_tsvs.") + self.outputFile = os.path.join(self.tmpDir, "output.tsv") + self.options = OptionsTuple(open(self.outputFile, "w")) + self.inputs = [os.path.join(self.testDataDir, f"rxn{i+1}.joined_filtered_cell_metadata.tsv") for i in range(2)] + self.index_cols = ["PREFIX", "CELL_BARCODE"] + + def tearDown(self): + shutil.rmtree(self.tmpDir) + + def test_basic(self): + options = self.options._replace(index_col=self.index_cols, input=[open(f) for f in self.inputs]) + self.assertEqual(dropseq_aggregation.cat_tsvs.run(options), 0) + outDf = pd.read_csv(self.outputFile, sep="\t") + inDfs = [pd.read_csv(f, sep="\t") for f in self.inputs] + self.assertEqual(len(outDf), sum(len(df) for df in inDfs)) + self.assertEqual(set(outDf.columns), set.union(*[set(df.columns) for df in inDfs])) + + def test_duplicate_keys(self): + options = self.options._replace(index_col=self.index_cols, input=[open(self.inputs[0]), open(self.inputs[0])]) + self.assertNotEqual(dropseq_aggregation.cat_tsvs.run(options), 0) + + def test_fewer_columns(self): + dfToClip = pd.read_csv(self.inputs[0], sep="\t", index_col=self.index_cols) + dfToClip = dfToClip.drop(columns="doublet", axis=1) + clippedFile = os.path.join(self.tmpDir, "clipped.tsv") + dfToClip.to_csv(clippedFile, sep="\t") + inputs = [clippedFile, self.inputs[1]] + options = self.options._replace(index_col=self.index_cols, input=[open(f) for f in inputs]) + self.assertEqual(dropseq_aggregation.cat_tsvs.run(options), 0) + outDf = pd.read_csv(self.outputFile, sep="\t") + inDfs = [pd.read_csv(f, sep="\t") for f in inputs] + self.assertEqual(len(outDf), sum(len(df) for df in inDfs)) + self.assertEqual(set(outDf.columns), set.union(*[set(df.columns) for df in inDfs])) diff --git a/testdata/python/dropseq_aggregation/cat_tsvs/rxn1.joined_filtered_cell_metadata.tsv b/testdata/python/dropseq_aggregation/cat_tsvs/rxn1.joined_filtered_cell_metadata.tsv new file mode 100644 index 00000000..b332b824 --- /dev/null +++ b/testdata/python/dropseq_aggregation/cat_tsvs/rxn1.joined_filtered_cell_metadata.tsv @@ -0,0 +1,100 @@ +PREFIX CELL_BARCODE predClass max.prob doublet DONOR NUM_GENIC_READS NUM_TRANSCRIPTS NUM_GENES bestSample bestLikelihood pvalue num_retained_transcripts pct_coding pct_utr pct_intergenic pct_genic pct_intronic pct_mt pct_ribosomal frac_contamination BRAINBANK AGE SEX RACE ETHNICITY PMI HBCAC.Status +rxn1 TTCTAACCAATTCGTG glutamatergic 1.0 False donor7 183875 85098 9952 donor7 -1501.5 5e-324 85098 0.0922 0.0575 0.067 0.1497 0.7823 0.001 0 0.0028357159596906 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn1 CTCCTCCGTTGGACTT glutamatergic 1.0 False donor11 184191 84071 9887 donor11 -1465.0 5e-324 84071 0.1023 0.0583 0.0641 0.1606 0.7743 0.001 0 0.0030476235651266 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 AATTTCCGTGGCTTGC glutamatergic 1.0 False donor14 167443 75596 9891 donor14 -1548.2 5e-324 75596 0.1496 0.121 0.0623 0.2706 0.6548 0.0124 0 0.0030332603592435 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn1 CTGTAGAAGCTATCCA glutamatergic 1.0 False donor11 133341 60931 9429 donor11 -1015.1 5e-324 60931 0.111 0.073 0.0655 0.1841 0.7483 0.0021 0 0.0042978069745399 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 AAGGAATCAACAGCTT glutamatergic 1.0 False donor7 137069 60870 9170 donor7 -1060.6 5e-324 60870 0.0969 0.0614 0.0687 0.1583 0.7709 0.0022 0 0.0036990965038628 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn1 CTAACTTCACTGGACC glutamatergic 1.0 False donor15 132104 59619 9120 donor15 -1150.0 5e-324 59619 0.1021 0.0669 0.0728 0.169 0.7562 0.002 0 0.0056539577704393 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn1 CTTCTAAGTTGCAACT glutamatergic 1.0 False donor11 125192 59284 8093 donor11 -1050.7 5e-324 59284 0.0963 0.0556 0.0637 0.1519 0.784 0.0004 0 0.004784367708036 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 CGAGTTAAGATCCGAG glutamatergic 1.0 False donor10 131085 58989 8805 donor10 -1325.9 5e-324 58989 0.0931 0.0604 0.0776 0.1535 0.7688 0.0002 0 0.0044722719141323 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn1 TCATTCATCTCGCTCA gabaergic 1.0 False donor1 126308 58487 7889 donor1 -1030.0 5e-324 58487 0.0938 0.0557 0.0607 0.1495 0.7884 0.0014 0 0.006100669544234 +rxn1 AGGTCTAGTGCCTGCA glutamatergic 1.0 False donor19 127271 57173 8707 donor19 -1010.2 5e-324 57173 0.0982 0.0544 0.0806 0.1526 0.7662 0.0007 0 0.0048215839860748 Pittsburgh 27.0 Male White Not Hispanic or Latino 14.52 non-HBCAC archival +rxn1 GTCAAACCAAACTAGA glutamatergic 1.0 False donor2 127814 56970 8962 donor2 -1174.7 5e-324 56970 0.1327 0.1017 0.0695 0.2344 0.6849 0.0111 0 0.0041776643535108 Maryland 46.0 Male Black or African-American Not_Hispanic_Latino 41.0 non-HBCAC archival +rxn1 ATGCCTCCAACTAGAA glutamatergic 1.0 False donor15 122907 56564 8052 donor15 -997.23 5e-324 56564 0.099 0.0563 0.0692 0.1553 0.7754 0.0001 0 0.0062369331857552 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn1 CTACAGAGTCCATACA glutamatergic 1.0 False donor11 124628 56467 8734 donor11 -991.26 5e-324 56467 0.0959 0.0625 0.0702 0.1583 0.771 0.0005 0 0.0041971607442024 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 TTCTGTACAATAGTAG glutamatergic 1.0 False donor1 107543 56119 7822 donor1 -932.34 5e-324 56119 0.0868 0.0598 0.0806 0.1466 0.7633 0.0094 0 0.0051762954033788 +rxn1 GGGTGTCAGGGAACAA glutamatergic 1.0 False donor16 130569 56010 8097 donor16 -953.0 5e-324 56010 0.0946 0.0679 0.0725 0.1625 0.7592 0.0058 0 0.0044967385315394 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 ACCAAACGTCTTAGTG glutamatergic 1.0 False donor13 124963 55541 8293 donor13 -998.61 5e-324 55541 0.1009 0.0627 0.0669 0.1635 0.7664 0.0031 0 0.0042489870558284 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn1 ATTCTTGAGAAGTATC glutamatergic 1.0 False donor1 96665 52275 7463 donor1 -855.61 5e-324 52275 0.0801 0.0501 0.0775 0.1302 0.7896 0.0027 0 0.0049680219278209 +rxn1 CCGCAAGAGTCTACCA glutamatergic 1.0 False donor10 113400 51245 8474 donor10 -1163.3 5e-324 51245 0.1041 0.058 0.0712 0.1621 0.7662 0.0004 0 0.006359917010839 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn1 GTCTACCTCGTTAGAC glutamatergic 1.0 False donor7 107886 51203 8209 donor7 -857.22 5e-324 51203 0.1031 0.0661 0.0815 0.1692 0.7428 0.0065 0 0.0049168221393034 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn1 GCATTAGGTAGGAGGG glutamatergic 1.0 False donor14 112008 50555 8418 donor14 -1055.7 5e-324 50555 0.1122 0.0693 0.0659 0.1815 0.751 0.0016 0 0.0043524499763667 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn1 CTAAGTGAGCATCAGG glutamatergic 1.0 False donor10 110234 49917 8217 donor10 -1169.0 5e-324 49917 0.0956 0.0546 0.0667 0.1502 0.7829 0.0003 0 0.0052014827215114 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn1 ACTATGGGTGGAACAC glutamatergic 1.0 False donor18 111875 49370 8134 donor18 -879.67 5e-324 49370 0.1125 0.0682 0.0646 0.1807 0.7492 0.0056 0 0.0063199420336527 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn1 CTGTGAACACCACATA glutamatergic 1.0 False donor5 101690 47925 7661 donor5 -981.22 5e-324 47925 0.1113 0.0937 0.0706 0.205 0.7151 0.0093 0 0.005932256124121 Maryland 28.0 Female Black or African-American Not_Hispanic_Latino 32.0 non-HBCAC archival +rxn1 TTAATCCTCGACGTCG glutamatergic 1.0 False donor14 104657 47542 8462 donor14 -999.8 5e-324 47542 0.1058 0.0727 0.0709 0.1785 0.7493 0.0014 0 0.005314252238681 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn1 CAATGACTCACTGGGC glutamatergic 1.0 False donor17 104862 47105 8465 donor17 -965.01 5e-324 47105 0.1328 0.098 0.0711 0.2309 0.6863 0.0118 0 0.0044804192996175 Pittsburgh 67.0 Male Black or African-American Not Hispanic or Latino 10.87 non-HBCAC archival +rxn1 GCACTAACATGACAAA glutamatergic 1.0 False donor18 105156 46695 7810 donor18 -894.77 5e-324 46695 0.1007 0.0626 0.0652 0.1633 0.7691 0.0025 0 0.0062567835025219 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn1 CTTACCGTCGTTGCCT glutamatergic 1.0 False donor10 97536 45421 8248 donor10 -1074.8 5e-324 45421 0.0935 0.0552 0.0682 0.1488 0.7823 0.0008 0 0.0060180322128851 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn1 AACAAAGTCATTGCGA glutamatergic 1.0 False donor14 103499 45305 7975 donor14 -1004.6 5e-324 45305 0.1024 0.0657 0.0615 0.1681 0.7697 0.0007 0 0.0050729093464511 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn1 CCCTCAAGTCCATAGT glutamatergic 1.0 False donor7 98908 45318 7976 donor7 -772.85 5e-324 45318 0.0996 0.0592 0.0772 0.1588 0.7629 0.0011 0 0.0047655649500384 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn1 TTCCTTCAGCACGATG glutamatergic 1.0 False donor12 92598 44816 7308 donor12 -703.81 5e-324 44816 0.1001 0.0669 0.0707 0.1671 0.7556 0.0066 0 0.005988555205607 Pittsburgh 41.0 Female White Not Hispanic or Latino 26.12 non-HBCAC archival +rxn1 AAGGTAACAAGTGCAG glutamatergic 1.0 False donor5 94649 44336 7685 donor5 -920.12 5e-324 44336 0.1243 0.1087 0.0599 0.2329 0.6743 0.0329 0 0.0068545316070068 Maryland 28.0 Female Black or African-American Not_Hispanic_Latino 32.0 non-HBCAC archival +rxn1 TGCTTGCTCACGACTA glutamatergic 1.0 False donor1 97841 44207 7614 donor1 -728.63 5e-324 44207 0.1024 0.0674 0.0646 0.1698 0.7609 0.0047 0 0.0047055115273775 +rxn1 TTCCGTGAGCACTCCG glutamatergic 1.0 False donor14 95147 42381 7977 donor14 -931.22 5e-324 42381 0.1225 0.0615 0.0622 0.184 0.753 0.0008 0 0.0059575466166295 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn1 CGCGTGAAGACCAACG glutamatergic 1.0 False donor7 87171 42242 7667 donor7 -734.61 5e-324 42242 0.1027 0.0677 0.0774 0.1703 0.7326 0.0196 0 0.0060472011106144 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn1 TGATTTCGTCAGCTTA glutamatergic 1.0 False donor13 94252 42132 7866 donor13 -753.3 5e-324 42132 0.1123 0.0769 0.0618 0.1891 0.7465 0.0026 0 0.0060159954703092 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn1 CACACAATCCGCTGTT glutamatergic 1.0 False donor11 94531 41636 8204 donor11 -730.93 5e-324 41636 0.1043 0.0629 0.0709 0.1672 0.761 0.0009 0 0.0059923126507031 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 CATTCCGGTATGACAA glutamatergic 1.0 False donor13 92431 41154 7525 donor13 -742.45 5e-324 41154 0.0992 0.0587 0.0637 0.1579 0.7773 0.0011 0 0.0068536126260919 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn1 CTGTATTGTCTAACTG glutamatergic 1.0 False donor4 85880 40239 8042 donor4 -733.15 5e-324 40239 0.0963 0.0602 0.0923 0.1566 0.7508 0.0004 0 0.0081831850336446 Maryland 27.0 Male White Not_Hispanic_Latino 33.0 non-HBCAC archival +rxn1 GTCTAGAGTAGATGTA glutamatergic 1.0 False donor13 85965 40039 7435 donor13 -734.44 5e-324 40039 0.1045 0.0541 0.0699 0.1586 0.7707 0.0008 0 0.008297419131124 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn1 GATGATCCAATCTAGC gabaergic 1.0 False donor13 86047 39143 6752 donor13 -712.43 5e-324 39143 0.1007 0.0559 0.0599 0.1566 0.7832 0.0003 0 0.0101656340877482 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn1 AGGATAATCCCAGGCA glutamatergic 1.0 False donor16 87092 39271 7346 donor16 -727.32 5e-324 39271 0.1019 0.0734 0.0815 0.1753 0.741 0.0022 0 0.0068785878663733 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 CACTTCGCAGGGTCTC glutamatergic 1.0 False donor2 82929 38638 7181 donor2 -813.92 5e-324 38638 0.1247 0.1047 0.0604 0.2294 0.7029 0.0073 0 0.0071691034766298 Maryland 46.0 Male Black or African-American Not_Hispanic_Latino 41.0 non-HBCAC archival +rxn1 CAACAGTTCGAAGAAT glutamatergic 1.0 False donor6 87685 38265 7977 donor6 -647.21 5e-324 38265 0.1399 0.1078 0.0667 0.2477 0.6751 0.0106 0 0.0069293055123014 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn1 GCATGATGTTGTGTAC glutamatergic 1.0 False donor16 82530 37772 8212 donor16 -665.75 5e-324 37772 0.1635 0.1285 0.063 0.292 0.6257 0.0192 0 0.0062876535739654 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 GTTACCCCAGCTCATA glutamatergic 1.0 False donor7 81874 36985 7017 donor7 -642.41 5e-324 36985 0.1025 0.0593 0.0691 0.1618 0.7675 0.0015 0 0.0092153553537464 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn1 CGGACACAGGAATGTT glutamatergic 1.0 False donor15 84013 36911 7555 donor15 -686.43 5e-324 36911 0.1004 0.0574 0.0865 0.1578 0.7543 0.0014 0 0.0074753287262362 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn1 TCTACCGAGTCTAACC glutamatergic 1.0 False donor4 80877 36944 7908 donor4 -666.75 5e-324 36944 0.1106 0.0547 0.0959 0.1653 0.7384 0.0004 0 0.0061336489831055 Maryland 27.0 Male White Not_Hispanic_Latino 33.0 non-HBCAC archival +rxn1 TTCGATTTCCTGTAGA gabaergic 1.0 False donor19 79305 36421 7233 donor19 -652.99 5e-324 36421 0.1038 0.0769 0.0651 0.1807 0.7478 0.0065 0 0.0104064775567873 Pittsburgh 27.0 Male White Not Hispanic or Latino 14.52 non-HBCAC archival +rxn1 GACTCTCCATGGCCCA gabaergic 1.0 False donor16 79258 35847 7241 donor16 -598.91 5e-324 35847 0.1345 0.0815 0.0683 0.2161 0.7119 0.0038 0 0.0078602861808418 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 CTCATTAAGATCGGTG glutamatergic 1.0 False donor6 72684 35502 7182 donor6 -609.75 5e-324 35502 0.1133 0.0884 0.0662 0.2017 0.7272 0.0049 0 0.0074090642212094 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn1 GTCTCACGTGTAAATG gabaergic 1.0 False donor18 73760 35053 6641 donor18 -615.62 5e-324 35053 0.0962 0.059 0.0669 0.1552 0.7772 0.0007 0 0.0106686235217747 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn1 AGTCAACGTGGATGAC glutamatergic 1.0 False donor16 76145 35016 7429 donor16 -591.34 5e-324 35016 0.1152 0.0829 0.0908 0.198 0.7018 0.0094 0 0.007651759904778 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 GCCAGGTCAGCAGTAG glutamatergic 1.0 False donor5 73624 34997 6886 donor5 -703.69 5e-324 34997 0.1033 0.0644 0.0863 0.1676 0.7337 0.0124 0 0.0074588769143505 Maryland 28.0 Female Black or African-American Not_Hispanic_Latino 32.0 non-HBCAC archival +rxn1 AGTAGTCTCGGAGTAG glutamatergic 1.0 False donor9 74757 34571 6920 donor9 -606.88 5e-324 34571 0.1097 0.0707 0.0654 0.1804 0.7523 0.0018 0 0.0077779691177314 Maryland 43.0 Female White Not reported 18.0 non-HBCAC archival +rxn1 ACTATCTTCCGATGCG gabaergic 1.0 False donor10 76524 34368 7312 donor10 -806.02 5e-324 34368 0.1226 0.066 0.0591 0.1886 0.7511 0.0012 0 0.0113626556971492 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn1 GTGACGCGTTTCTATC glutamatergic 1.0 False donor3 73965 34168 6812 donor3 -600.74 5e-324 34168 0.1042 0.0657 0.0727 0.1699 0.7549 0.0026 0 0.0086749644587577 Maryland 55.0 Male White Not_Hispanic_Latino 26.0 non-HBCAC archival +rxn1 ACGGGTCGTTTGAAAG glutamatergic 1.0 False donor2 72148 33719 6917 donor2 -704.88 5e-324 33719 0.1258 0.0978 0.0599 0.2235 0.7051 0.0114 0 0.0083230398211869 Maryland 46.0 Male Black or African-American Not_Hispanic_Latino 41.0 non-HBCAC archival +rxn1 CCTCAGTCAAGTGGGT glutamatergic 1.0 False donor14 74444 33648 7123 donor14 -730.52 5e-324 33648 0.1174 0.0762 0.0654 0.1935 0.7377 0.0033 0 0.0095955730853005 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn1 GCTACAAAGAGTGAAG glutamatergic 1.0 False donor11 74849 33483 7605 donor11 -645.16 5e-324 33483 0.1028 0.0719 0.0637 0.1748 0.7607 0.0009 0 0.0077347083926031 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 CCGATCTGTGGCCTCA gabaergic 1.0 False donor16 67627 32474 6611 donor16 -581.1 5e-324 32474 0.1055 0.0804 0.0635 0.1859 0.7373 0.0133 0 0.0129183257849783 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 GATTCTTTCGAGAGCA glutamatergic 1.0 False donor2 67579 32486 6645 donor2 -692.01 5e-324 32486 0.1029 0.0719 0.0652 0.1748 0.7585 0.0015 0 0.0114417868662894 Maryland 46.0 Male Black or African-American Not_Hispanic_Latino 41.0 non-HBCAC archival +rxn1 GATGACTTCGCAACAT gabaergic 0.999 False donor14 72671 32348 6964 donor14 -703.97 5e-324 32348 0.1306 0.1264 0.0613 0.2571 0.6743 0.0073 0 0.0107645259938838 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn1 GATGGAGCAAAGGCAC glutamatergic 1.0 False donor16 72290 32240 7136 donor16 -542.54 5e-324 32240 0.1224 0.0987 0.0725 0.2211 0.6997 0.0067 0 0.008213615528963 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 TGCTCCAAGGGAGTTC glutamatergic 1.0 False donor16 69397 32218 7066 donor16 -549.5 5e-324 32218 0.1274 0.0914 0.065 0.2187 0.7082 0.0081 0 0.0085854078838046 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 TAGTGCATCAGCTAGT glutamatergic 1.0 False donor16 72892 32172 7257 donor16 -563.61 5e-324 32172 0.1346 0.0991 0.0661 0.2337 0.6968 0.0034 0 0.0096961861667743 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 AAGTGAAGTGTCATCA glutamatergic 1.0 False donor8 70961 31606 6810 donor8 -747.18 5e-324 31606 0.1017 0.0598 0.0683 0.1615 0.7695 0.0007 0 0.0110763454317897 Maryland 32.0 Male Black or African-American Not reported 23.0 non-HBCAC archival +rxn1 TGCACGGGTTGCATTG glutamatergic 1.0 False donor7 71279 31458 6928 donor7 -603.82 5e-324 31458 0.1079 0.0695 0.0673 0.1775 0.7525 0.0027 0 0.0091968503937007 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn1 ATTTACCTCTTCCCAG glutamatergic 1.0 False donor10 67284 31341 7036 donor10 -754.89 5e-324 31341 0.1123 0.0564 0.0704 0.1687 0.7605 0.0004 0 0.0116367076631977 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn1 AAGCGTTGTCTTCATT glutamatergic 1.0 False donor11 66513 31157 7054 donor11 -561.19 5e-324 31157 0.1116 0.0787 0.0594 0.1903 0.7473 0.003 0 0.0102919221117499 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 TGATTCTCACAGTCCG glutamatergic 1.0 False donor11 68421 30708 6773 donor11 -600.05 5e-324 30708 0.108 0.0762 0.0587 0.1842 0.7539 0.0032 0 0.0104408352668214 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 CAGGGCTAGATAGCAT glutamatergic 1.0 False donor12 62114 30600 6335 donor12 -511.59 5e-324 30600 0.0931 0.0573 0.0826 0.1503 0.7556 0.0116 0 0.0087784652262641 Pittsburgh 41.0 Female White Not Hispanic or Latino 26.12 non-HBCAC archival +rxn1 CCTCTCCTCGCCAATA glutamatergic 1.0 False donor10 66314 30422 6864 donor10 -690.71 5e-324 30422 0.1122 0.0545 0.0802 0.1667 0.753 0.0001 0 0.0103126321610982 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn1 CGTTCTGGTAGTTAGA glutamatergic 1.0 False donor10 65868 30341 6813 donor10 -678.15 5e-324 30341 0.1117 0.0692 0.0658 0.181 0.7519 0.0013 0 0.0093381656708133 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn1 ACGTCCTGTCAGGTGA glutamatergic 1.0 False donor9 61821 29789 6346 donor9 -492.97 5e-324 29789 0.1139 0.0736 0.0728 0.1874 0.7381 0.0017 0 0.0116456536164565 Maryland 43.0 Female White Not reported 18.0 non-HBCAC archival +rxn1 CAACGATCAGAGTGTG glutamatergic 1.0 False donor13 66470 29741 6861 donor13 -534.29 5e-324 29741 0.122 0.093 0.0691 0.215 0.7075 0.0084 0 0.0100522584295842 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn1 GCACGGTCAGGTGAGT glutamatergic 1.0 False donor11 64055 29484 6116 donor11 -551.01 5e-324 29484 0.1184 0.0777 0.0568 0.1961 0.746 0.0011 0 0.0142427281845536 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 TGAGGGAAGCTAATCC glutamatergic 1.0 False donor9 66177 29291 6666 donor9 -502.49 5e-324 29291 0.1183 0.0775 0.0759 0.1958 0.726 0.0023 0 0.0104391891891892 Maryland 43.0 Female White Not reported 18.0 non-HBCAC archival +rxn1 ATCCCTGAGCGCCTAC glutamatergic 0.999 False donor6 62836 28780 6737 donor6 -526.11 5e-324 28780 0.1303 0.0892 0.0601 0.2195 0.7184 0.0019 0 0.0117436989217774 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn1 CACACAACACGAAAGC glutamatergic 1.0 False donor18 65728 28363 6967 donor18 -532.77 5e-324 28363 0.1264 0.1035 0.0654 0.2299 0.6996 0.0052 0 0.0121207899411375 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn1 AGGGCCTTCATGGTAC glutamatergic 1.0 False donor6 61627 28175 7238 donor6 -534.06 5e-324 28175 0.1278 0.0702 0.0738 0.1979 0.7277 0.0005 0 0.0109870822802584 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn1 TACAACGTCAAATGAG glutamatergic 1.0 False donor4 61520 27777 6787 donor4 -556.12 5e-324 27777 0.1055 0.0689 0.0836 0.1744 0.739 0.003 0 0.0125137758185503 Maryland 27.0 Male White Not_Hispanic_Latino 33.0 non-HBCAC archival +rxn1 TTAGGCAGTTCAAGGG glutamatergic 1.0 False donor7 61675 27643 6612 donor7 -503.43 5e-324 27643 0.1163 0.0832 0.0613 0.1995 0.7326 0.0066 0 0.0105945094670532 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn1 CATCGGGTCTCTGCCA glutamatergic 1.0 False donor14 58974 27190 6217 donor14 -639.55 5e-324 27190 0.1168 0.0713 0.0639 0.1881 0.7454 0.0026 0 0.0143193764727206 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn1 AGAACAAAGGACAACC gabaergic 1.0 False donor6 57123 26890 5921 donor6 -485.31 5e-324 26890 0.1044 0.0656 0.0677 0.17 0.7518 0.0105 0 0.0156673255728823 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn1 TGGGATTCAAGTCGTT gabaergic 1.0 False donor14 59830 26821 6083 donor14 -611.57 5e-324 26821 0.1069 0.0612 0.0591 0.1681 0.7715 0.0013 0 0.0175457875457875 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn1 TGGGAGACAAAGAACT glutamatergic 1.0 False donor11 61298 26992 6718 donor11 -517.57 5e-324 26992 0.1027 0.0594 0.0628 0.1621 0.7744 0.0007 0 0.0101217544374358 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 GTTTGGAAGATACAGT glutamatergic 1.0 False donor15 57669 26767 6870 donor15 -514.8 5e-324 26767 0.1321 0.1079 0.0725 0.2399 0.6842 0.0034 0 0.0141431254834076 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn1 ATTTACCGTGACTGAG gabaergic 1.0 False donor11 57651 26556 6832 donor11 -485.14 5e-324 26556 0.1214 0.0654 0.0624 0.1868 0.7496 0.0012 0 0.0155693950177936 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 GAGTTGTCAGCTATTG gabaergic 0.998 False donor4 58283 26459 6704 donor4 -479.09 5e-324 26459 0.1118 0.0784 0.0998 0.1902 0.7045 0.0055 0 0.011654402151582 Maryland 27.0 Male White Not_Hispanic_Latino 33.0 non-HBCAC archival +rxn1 GCGTGCAAGCAGGCTA glutamatergic 1.0 False donor18 56769 26355 6249 donor18 -481.82 5e-324 26355 0.1214 0.071 0.066 0.1924 0.7398 0.0017 0 0.0151345291479821 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn1 GCCGTGATCCACCTGT glutamatergic 1.0 False donor7 55512 26205 6448 donor7 -455.85 5e-324 26205 0.1047 0.0605 0.069 0.1651 0.765 0.0008 0 0.013217352010845 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn1 CATGGTACACGCTGTG glutamatergic 1.0 False donor6 59224 26187 6494 donor6 -483.76 5e-324 26187 0.1419 0.0963 0.0662 0.2382 0.6951 0.0005 0 0.0112889828588688 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn1 TTCTAGTAGAGTTCGG glutamatergic 1.0 False donor11 54097 25908 6986 donor11 -461.22 5e-324 25908 0.1533 0.1323 0.068 0.2856 0.6273 0.0192 0 0.0130661689078512 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn1 AAACCCACACAGCTTA gabaergic 1.0 False donor16 57102 25734 5738 donor16 -449.83 5e-324 25734 0.128 0.1058 0.061 0.2338 0.6957 0.0095 0 0.0174862553451436 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 TAGGGTTAGTTCAACC gabaergic 0.999 False donor10 56449 25689 6089 donor10 -620.58 5e-324 25689 0.103 0.0713 0.0656 0.1742 0.7597 0.0005 0 0.0178168610208373 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn1 TCAGTCCCAAGCGCAA glutamatergic 1.0 False donor16 59196 25811 6631 donor16 -425.13 5e-324 25811 0.1388 0.0929 0.0695 0.2317 0.6943 0.0045 0 0.0114515511298353 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn1 GTTATGGTCCGTGGCA glutamatergic 1.0 False donor18 56151 25249 6801 donor18 -474.05 5e-324 25249 0.1521 0.114 0.058 0.2661 0.6662 0.0097 0 0.0123606493252494 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn1 ATTCTTGAGTCCGCGT glutamatergic 1.0 False donor17 53483 25197 6774 donor17 -533.79 5e-324 25197 0.1365 0.109 0.0694 0.2455 0.6793 0.0059 0 0.0119598462865658 Pittsburgh 67.0 Male Black or African-American Not Hispanic or Latino 10.87 non-HBCAC archival +rxn1 ACCGTTCTCCGCGATG glutamatergic 1.0 False donor17 56450 25083 6124 donor17 -548.67 5e-324 25083 0.1278 0.0735 0.0601 0.2013 0.7365 0.002 0 0.0136065122497936 Pittsburgh 67.0 Male Black or African-American Not Hispanic or Latino 10.87 non-HBCAC archival diff --git a/testdata/python/dropseq_aggregation/cat_tsvs/rxn2.joined_filtered_cell_metadata.tsv b/testdata/python/dropseq_aggregation/cat_tsvs/rxn2.joined_filtered_cell_metadata.tsv new file mode 100644 index 00000000..7073cdb6 --- /dev/null +++ b/testdata/python/dropseq_aggregation/cat_tsvs/rxn2.joined_filtered_cell_metadata.tsv @@ -0,0 +1,100 @@ +PREFIX CELL_BARCODE predClass max.prob doublet DONOR NUM_GENIC_READS NUM_TRANSCRIPTS NUM_GENES bestSample bestLikelihood pvalue num_retained_transcripts pct_coding pct_utr pct_intergenic pct_genic pct_intronic pct_mt pct_ribosomal frac_contamination BRAINBANK AGE SEX RACE ETHNICITY PMI HBCAC.Status +rxn2 AACGAAACACAACGTT glutamatergic 1.0 False donor6 222398 86298 10466 donor6 -1500.4 5e-324 86298 0.1237 0.0702 0.0664 0.1939 0.7374 0.0023 0 0.0022660531366337 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn2 GAAACCTGTATCCTTT glutamatergic 1.0 False donor7 168959 67274 9438 donor7 -1109.6 5e-324 67274 0.1026 0.0732 0.0714 0.1758 0.7475 0.0053 0 0.0035400589516093 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 AATTCCTTCTTCACGC glutamatergic 1.0 False donor18 156534 66944 8969 donor18 -1150.9 5e-324 66944 0.0943 0.0509 0.0733 0.1451 0.781 0.0006 0 0.0035129502828222 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn2 CCTCTCCCAGAGTAAT glutamatergic 1.0 False donor12 148355 63654 8588 donor12 -1033.1 5e-324 63654 0.0924 0.0628 0.0742 0.1552 0.7664 0.0042 0 0.0034598825831702 Pittsburgh 41.0 Female White Not Hispanic or Latino 26.12 non-HBCAC archival +rxn2 ATCCTATAGGAAACGA glutamatergic 1.0 False donor15 136443 57836 9120 donor15 -1011.5 5e-324 57836 0.0967 0.0559 0.0696 0.1526 0.7764 0.0014 0 0.0048864418444597 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn2 CTGTATTTCCGCAACG glutamatergic 1.0 False donor11 133452 54507 8808 donor11 -1001.9 5e-324 54507 0.1067 0.0699 0.0658 0.1766 0.7542 0.0034 0 0.0050562207943925 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn2 CACACAAGTCTCCTGT glutamatergic 1.0 False donor16 132479 53992 8347 donor16 -844.9 5e-324 53992 0.099 0.0727 0.0776 0.1717 0.7458 0.0049 0 0.0038192586579087 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 GCGGAAAGTACAAACA glutamatergic 1.0 False donor7 134893 53288 9066 donor7 -930.94 5e-324 53288 0.1016 0.0728 0.0704 0.1744 0.7531 0.0021 0 0.0041487572416371 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 TCGCTCAAGTCACACT glutamatergic 1.0 False donor9 116231 51682 7274 donor9 -818.03 5e-324 51682 0.0935 0.0594 0.0654 0.1529 0.7788 0.0029 0 0.0051779561509884 Maryland 43.0 Female White Not reported 18.0 non-HBCAC archival +rxn2 TTGACCCTCGTGGCGT glutamatergic 1.0 False donor14 125222 51629 8526 donor14 -1036.4 5e-324 51629 0.1239 0.0961 0.0612 0.22 0.7113 0.0076 0 0.0049148099606815 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn2 CTTACCGCATGACACT glutamatergic 1.0 False donor15 125197 51204 8348 donor15 -936.5 5e-324 51204 0.1021 0.0652 0.0747 0.1673 0.7542 0.0038 0 0.0054772171075632 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn2 ATGAGTCGTGGTCTCG glutamatergic 1.0 False donor7 123621 50966 8499 donor7 -834.0 5e-324 50966 0.1006 0.0718 0.0733 0.1725 0.7483 0.0059 0 0.0047258240899859 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 CACCGTTCATGGCTGC gabaergic 1.0 False donor7 126238 50939 8238 donor7 -858.22 5e-324 50939 0.1151 0.0922 0.0597 0.2073 0.7224 0.0106 0 0.0051170875568836 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 GGTAACTAGAGCAACC glutamatergic 1.0 False donor13 128779 50229 8361 donor13 -919.36 5e-324 50229 0.1072 0.0706 0.0616 0.1778 0.7597 0.001 0 0.0049525545276253 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn2 CATGCGGTCCTTCTTC glutamatergic 1.0 False donor16 120874 49604 8288 donor16 -819.73 5e-324 49604 0.1223 0.0812 0.0693 0.2035 0.7229 0.0043 0 0.0050346003409889 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 ATCGTGAGTTGCATCA glutamatergic 1.0 False donor18 117863 48731 7934 donor18 -838.57 5e-324 48731 0.1001 0.0651 0.0663 0.1652 0.7676 0.0009 0 0.0051852607941206 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn2 TTCTAACCATCGATAC glutamatergic 1.0 False donor3 119642 48715 7610 donor3 -795.26 5e-324 48715 0.1033 0.0749 0.0732 0.1782 0.7449 0.0037 0 0.0051666394380003 Maryland 55.0 Male White Not_Hispanic_Latino 26.0 non-HBCAC archival +rxn2 CATACCCAGTCTTGGT glutamatergic 1.0 False donor19 119877 48272 7922 donor19 -876.18 5e-324 48272 0.0959 0.0587 0.0642 0.1546 0.7808 0.0005 0 0.0059922162963572 Pittsburgh 27.0 Male White Not Hispanic or Latino 14.52 non-HBCAC archival +rxn2 TCATATCGTATCGAAA glutamatergic 1.0 False donor16 113888 46399 8777 donor16 -744.51 5e-324 46399 0.1527 0.1282 0.0726 0.2808 0.6348 0.0118 0 0.0059558240675279 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 ACCTGTCAGGAGATAG glutamatergic 1.0 False donor16 111624 46251 7726 donor16 -770.39 5e-324 46251 0.1004 0.0616 0.0779 0.1621 0.7572 0.0029 0 0.0057397136592286 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 GAATCGTCAAGCCCAC glutamatergic 1.0 False donor10 118614 46197 8447 donor10 -1030.1 5e-324 46197 0.1107 0.0579 0.0699 0.1686 0.7613 0.0002 0 0.0051468688086828 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn2 ATCACTTGTCGGATTT glutamatergic 1.0 False donor10 104772 42742 7782 donor10 -960.25 5e-324 42742 0.1001 0.0618 0.0665 0.162 0.7704 0.0011 0 0.0064390153188126 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn2 CACCGTTGTCTAGGCC glutamatergic 1.0 False donor2 103160 42674 7916 donor2 -837.71 5e-324 42674 0.1603 0.1371 0.0515 0.2974 0.6349 0.0162 0 0.0055462341536166 Maryland 46.0 Male Black or African-American Not_Hispanic_Latino 41.0 non-HBCAC archival +rxn2 ACGGGTCTCGCTAATG glutamatergic 1.0 False donor16 103155 41852 7758 donor16 -738.54 5e-324 41852 0.1153 0.071 0.0753 0.1864 0.7364 0.002 0 0.006339181841924 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 TTAGGGTCACGCGCTA glutamatergic 1.0 False donor11 100810 41429 7470 donor11 -715.8 5e-324 41429 0.0942 0.0527 0.0776 0.1469 0.7741 0.0014 0 0.0073081899650165 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn2 GGGATCCGTAGAATGT glutamatergic 1.0 False donor2 98472 40283 7595 donor2 -795.07 5e-324 40283 0.1183 0.1075 0.0646 0.2258 0.6993 0.0102 0 0.0075634392707563 Maryland 46.0 Male Black or African-American Not_Hispanic_Latino 41.0 non-HBCAC archival +rxn2 TCGAACATCCATAAGC gabaergic 1.0 False donor5 97495 40042 7913 donor5 -815.31 5e-324 40042 0.1425 0.139 0.0674 0.2815 0.6423 0.0088 0 0.0073626019484865 Maryland 28.0 Female Black or African-American Not_Hispanic_Latino 32.0 non-HBCAC archival +rxn2 GTAACCATCTCCACTG glutamatergic 1.0 False donor16 99784 39668 8091 donor16 -607.13 5e-324 39668 0.1387 0.1007 0.0727 0.2394 0.683 0.005 0 0.0061632509896276 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 TAAGTCGTCCCTTGGT glutamatergic 1.0 False donor10 95847 38847 7957 donor10 -957.02 5e-324 38847 0.1017 0.0611 0.0665 0.1628 0.77 0.0007 0 0.0077141178574164 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn2 GATCGTACAAAGCTAA glutamatergic 1.0 False donor15 96167 38638 7382 donor15 -793.98 5e-324 38638 0.1018 0.0666 0.0729 0.1684 0.7571 0.0016 0 0.0097390947767697 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn2 GTTGTGAAGTATGTAG glutamatergic 1.0 False donor3 92606 37727 7061 donor3 -609.65 5e-324 37727 0.0981 0.0661 0.0614 0.1642 0.7739 0.0006 0 0.0083324571548733 Maryland 55.0 Male White Not_Hispanic_Latino 26.0 non-HBCAC archival +rxn2 AGAACAATCTCCGTGT glutamatergic 1.0 False donor15 93081 37513 7296 donor15 -752.08 5e-324 37513 0.1143 0.0675 0.073 0.1818 0.7441 0.001 0 0.0103938586540745 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn2 GTTAGACCATTCTGTT glutamatergic 1.0 False donor15 90686 36821 7451 donor15 -647.04 5e-324 36821 0.123 0.0847 0.0581 0.2078 0.7304 0.0037 0 0.0082152669288369 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn2 ACATCGAGTACGTTCA glutamatergic 1.0 False donor13 89007 36365 7003 donor13 -643.72 5e-324 36365 0.1047 0.0688 0.0696 0.1735 0.7555 0.0014 0 0.008209240168003 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn2 TACTTACAGTGCACCC glutamatergic 1.0 False donor14 88664 36289 6668 donor14 -826.3 5e-324 36289 0.1032 0.0758 0.0672 0.1789 0.7506 0.0032 0 0.0097958960925561 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn2 AGGTCTACAGAGTCAG glutamatergic 1.0 False donor7 87274 36183 8053 donor7 -668.25 5e-324 36183 0.1333 0.0929 0.0739 0.2262 0.6898 0.0101 0 0.0063982864674868 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 GTTATGGAGGTACATA glutamatergic 1.0 False donor7 86409 35839 7405 donor7 -642.96 5e-324 35839 0.105 0.0664 0.0672 0.1714 0.7601 0.0014 0 0.0084659012311523 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 CTCCCAACAGAGAGGG glutamatergic 1.0 False donor5 82868 35850 7114 donor5 -713.27 5e-324 35850 0.1272 0.1092 0.0603 0.2365 0.6861 0.0171 0 0.0078321755735754 Maryland 28.0 Female Black or African-American Not_Hispanic_Latino 32.0 non-HBCAC archival +rxn2 GACTATGCACGTCTCT glutamatergic 1.0 False donor7 88488 35754 7045 donor7 -632.68 5e-324 35754 0.0975 0.064 0.0733 0.1615 0.7639 0.0013 0 0.0096393551603789 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 TCGACCTAGAGAGGTA glutamatergic 1.0 False donor17 85723 35732 7389 donor17 -702.98 5e-324 35732 0.1141 0.0741 0.0665 0.1882 0.7444 0.0009 0 0.0072789909429349 Pittsburgh 67.0 Male Black or African-American Not Hispanic or Latino 10.87 non-HBCAC archival +rxn2 ACTTCGCGTGTTTACG glutamatergic 1.0 False donor11 84336 35660 7429 donor11 -591.16 5e-324 35660 0.1084 0.0732 0.0715 0.1815 0.7456 0.0014 0 0.0078183689936284 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn2 TCAGCAAAGTTGCTCA glutamatergic 1.0 False donor18 88959 35550 7275 donor18 -655.31 5e-324 35550 0.1073 0.0702 0.0677 0.1775 0.7519 0.0029 0 0.0096113664855829 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn2 GCGGAAATCTGCGGGT glutamatergic 1.0 False donor4 86224 35365 7589 donor4 -663.12 5e-324 35365 0.1019 0.0636 0.0799 0.1656 0.7543 0.0002 0 0.0079109041434062 Maryland 27.0 Male White Not_Hispanic_Latino 33.0 non-HBCAC archival +rxn2 GTTGAACCAAGCTACT glutamatergic 1.0 False donor15 85472 34714 6838 donor15 -628.77 5e-324 34714 0.1003 0.0558 0.0822 0.1561 0.7612 0.0005 0 0.0115885082998776 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn2 TAATCTCAGAAGGCTC glutamatergic 1.0 False donor14 84811 34380 7193 donor14 -729.11 5e-324 34380 0.1205 0.0805 0.0558 0.2009 0.7398 0.0034 0 0.0086219325816776 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn2 GCTGGGTAGTGAGGTC glutamatergic 1.0 False donor17 77260 33821 7110 donor17 -676.72 5e-324 33821 0.1285 0.1283 0.0613 0.2567 0.6647 0.0172 0 0.0090245831990389 Pittsburgh 67.0 Male Black or African-American Not Hispanic or Latino 10.87 non-HBCAC archival +rxn2 ACTACGACATACAGAA glutamatergic 1.0 False donor11 83836 33693 7040 donor11 -588.36 5e-324 33693 0.1011 0.0747 0.0733 0.1758 0.7503 0.0006 0 0.0103101868170603 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn2 TCTGGCTAGGAAGTAG glutamatergic 1.0 False donor16 81342 33567 7056 donor16 -580.31 5e-324 33567 0.112 0.0744 0.063 0.1865 0.7452 0.0053 0 0.008506867523261 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 TAGACCAAGGTAACTA glutamatergic 1.0 False donor11 81098 32561 6771 donor11 -585.45 5e-324 32561 0.1128 0.0765 0.0659 0.1893 0.7421 0.0028 0 0.0113857177556473 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn2 CCGATCTCATTCTCTA glutamatergic 1.0 False donor14 73964 31479 6817 donor14 -653.48 5e-324 31479 0.106 0.0663 0.0794 0.1723 0.7466 0.0017 0 0.0107476194965589 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn2 CCGGACACAGCATGCC glutamatergic 1.0 False donor9 72147 31043 6174 donor9 -513.13 5e-324 31043 0.1065 0.0648 0.0659 0.1713 0.7616 0.0012 0 0.0112119764293678 Maryland 43.0 Female White Not reported 18.0 non-HBCAC archival +rxn2 GGCTGTGAGCCTTCTC glutamatergic 1.0 False donor6 77247 30950 6703 donor6 -531.57 5e-324 30950 0.1222 0.0902 0.0637 0.2123 0.7202 0.0038 0 0.0099484981286587 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn2 TGTTGAGCAAACGAGC glutamatergic 1.0 False donor11 76605 30844 6945 donor11 -556.19 5e-324 30844 0.0985 0.0687 0.0685 0.1672 0.7627 0.0017 0 0.0111250040075663 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn2 GCAGCCAAGGTTACCT glutamatergic 1.0 False donor6 77255 30841 6483 donor6 -513.12 5e-324 30841 0.1119 0.0856 0.0593 0.1975 0.739 0.0043 0 0.0090289827131931 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn2 GTTGTGATCTGGAAGG glutamatergic 1.0 False donor6 74430 30597 7245 donor6 -497.51 5e-324 30597 0.1658 0.1329 0.0527 0.2988 0.6434 0.0051 0 0.0144624106165046 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn2 TCCTTTCAGCTCCGAC glutamatergic 1.0 False donor10 76088 30702 6697 donor10 -703.1 5e-324 30702 0.1049 0.0637 0.0731 0.1686 0.7572 0.0011 0 0.0103471617831931 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn2 CAACCTCTCTGGCCAG glutamatergic 1.0 False donor13 74228 30623 6257 donor13 -518.23 5e-324 30623 0.1106 0.0579 0.0738 0.1685 0.7573 0.0004 0 0.0117468615871171 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn2 GGTCTGGAGCGCTGCT glutamatergic 1.0 False donor16 75344 30608 7354 donor16 -511.62 5e-324 30608 0.1565 0.1395 0.0625 0.296 0.6336 0.0079 0 0.0095139473173256 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 CTTCTAAGTAACTAAG gabaergic 1.0 False donor14 72906 30370 6718 donor14 -670.26 5e-324 30370 0.107 0.08 0.0556 0.187 0.7553 0.002 0 0.0121328432488697 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn2 AAAGAACTCCGCAAAT glutamatergic 1.0 False donor3 76119 30378 6696 donor3 -549.63 5e-324 30378 0.1092 0.0759 0.0716 0.1851 0.7417 0.0016 0 0.0110040369839823 Maryland 55.0 Male White Not_Hispanic_Latino 26.0 non-HBCAC archival +rxn2 CTTAGGAAGCATGAAT glutamatergic 1.0 False donor17 74912 30297 6898 donor17 -629.66 5e-324 30297 0.1221 0.0903 0.0681 0.2123 0.7185 0.001 0 0.0089951589689912 Pittsburgh 67.0 Male Black or African-American Not Hispanic or Latino 10.87 non-HBCAC archival +rxn2 ATGACCAGTGTACAGG glutamatergic 1.0 False donor16 74810 30017 7056 donor16 -503.41 5e-324 30017 0.1276 0.0877 0.074 0.2153 0.7101 0.0006 0 0.0091437248299993 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 TCGGGTGAGTGGAAAG glutamatergic 1.0 False donor4 70180 29472 7036 donor4 -550.97 5e-324 29472 0.1122 0.0696 0.081 0.1819 0.7359 0.0012 0 0.009610860944956 Maryland 27.0 Male White Not_Hispanic_Latino 33.0 non-HBCAC archival +rxn2 CCTACGTGTTAGAAGT gabaergic 1.0 False donor13 71335 28996 6455 donor13 -507.4 5e-324 28996 0.1111 0.0694 0.0551 0.1805 0.7627 0.0017 0 0.0137750416652495 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn2 TTCATTGAGAGGATGA glutamatergic 1.0 False donor3 69744 28909 6768 donor3 -513.88 5e-324 28909 0.1055 0.076 0.075 0.1815 0.7413 0.0022 0 0.0121309458720612 Maryland 55.0 Male White Not_Hispanic_Latino 26.0 non-HBCAC archival +rxn2 ACCGTTCCAGTAGAGC gabaergic 0.999 False donor16 71749 28814 6226 donor16 -502.36 5e-324 28814 0.1058 0.0889 0.0559 0.1947 0.7461 0.0033 0 0.013286761180741 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 CACTAAGTCTGCGATA glutamatergic 1.0 False donor5 68528 28859 6499 donor5 -557.94 5e-324 28859 0.1171 0.1052 0.0675 0.2223 0.6928 0.0174 0 0.0116442343915888 Maryland 28.0 Female Black or African-American Not_Hispanic_Latino 32.0 non-HBCAC archival +rxn2 TGCCGAGGTCTACTGA glutamatergic 1.0 False donor17 71177 28862 6659 donor17 -602.8 5e-324 28862 0.1222 0.0807 0.0633 0.2029 0.7305 0.0033 0 0.0089279582446261 Pittsburgh 67.0 Male Black or African-American Not Hispanic or Latino 10.87 non-HBCAC archival +rxn2 TGGGAAGAGTGATGGC glutamatergic 1.0 False donor16 69927 28806 7333 donor16 -491.52 5e-324 28806 0.1701 0.1408 0.067 0.3109 0.6095 0.0127 0 0.0101711222596386 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 GAGGCCTAGCGTTACT glutamatergic 1.0 False donor6 71445 28659 6347 donor6 -507.88 5e-324 28659 0.1209 0.0816 0.0675 0.2025 0.7257 0.0043 0 0.0113836282727932 Maryland 47.0 Male White Not reported 22.0 non-HBCAC archival +rxn2 CAAGCTACATCTTCGC gabaergic 1.0 False donor13 72083 28129 6194 donor13 -527.87 5e-324 28129 0.1024 0.0726 0.05 0.1751 0.7732 0.0017 0 0.0163997482341423 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn2 ATCGTCCCATGCCGCA gabaergic 1.0 False donor13 69742 28083 6260 donor13 -551.48 5e-324 28083 0.1103 0.0656 0.0614 0.1758 0.7617 0.0011 0 0.0145624254333637 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn2 TCAGGTAGTGCGGATA glutamatergic 1.0 False donor7 67276 28057 6438 donor7 -527.17 5e-324 28057 0.109 0.0723 0.0769 0.1813 0.7375 0.0043 0 0.0125294759441101 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 GCGATCGGTGCCCACA glutamatergic 1.0 False donor18 60675 28046 6535 donor18 -485.16 5e-324 28046 0.1164 0.0643 0.0655 0.1806 0.7526 0.0013 0 0.011942927602607 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn2 CATTGCCCAAGCCTGC polydendrocyte 1.0 False donor13 72121 27704 6006 donor13 -521.94 5e-324 27704 0.0957 0.0598 0.05 0.1555 0.7928 0.0016 0 0.0194315647895799 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn2 ATTGGGTTCCAATCCC glutamatergic 1.0 False donor14 69691 27901 6758 donor14 -565.57 5e-324 27901 0.1215 0.0681 0.0614 0.1896 0.747 0.002 0 0.0108483709717446 Pittsburgh 44.0 Male Black or African-American Not Hispanic or Latino 10.57 non-HBCAC archival +rxn2 GCAGCCAAGCAATTAG glutamatergic 1.0 False donor18 70975 27763 6441 donor18 -507.38 5e-324 27763 0.1066 0.076 0.0742 0.1826 0.7413 0.0019 0 0.0123092248034438 Pittsburgh 53.0 Male White Not Hispanic or Latino 22.73 non-HBCAC archival +rxn2 TGATGCAAGTATAACG glutamatergic 1.0 False donor9 63835 27339 6004 donor9 -471.13 5e-324 27339 0.1158 0.0684 0.0725 0.1842 0.7366 0.0067 0 0.0140646976090014 Maryland 43.0 Female White Not reported 18.0 non-HBCAC archival +rxn2 CAGGGCTTCTCAGTCC gabaergic 1.0 False donor11 68403 27382 6477 donor11 -514.49 5e-324 27382 0.1076 0.067 0.0664 0.1746 0.7582 0.0008 0 0.0114444564785733 Pittsburgh 58.0 Male White Not Hispanic or Latino 14.37 non-HBCAC archival +rxn2 TCTTAGTTCTGACCCT glutamatergic 1.0 False donor12 63616 27288 6154 donor12 -455.74 5e-324 27288 0.1113 0.0936 0.0785 0.2049 0.7088 0.0078 0 0.0121275748470477 Pittsburgh 41.0 Female White Not Hispanic or Latino 26.12 non-HBCAC archival +rxn2 TCTCTGGAGGCTTTCA gabaergic 1.0 False donor16 64407 27094 5932 donor16 -465.35 5e-324 27094 0.1089 0.0841 0.0594 0.1931 0.7421 0.0054 0 0.0187954948756021 Pittsburgh 65.0 Male White Not Hispanic or Latino 23.72 non-HBCAC archival +rxn2 TCTCACGAGATTGGGC glutamatergic 1.0 False donor7 65011 26900 6693 donor7 -489.85 5e-324 26900 0.1146 0.0649 0.0719 0.1795 0.7474 0.0012 0 0.0135318493527449 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 GTCATTTCAAGGAGTC glutamatergic 1.0 False donor10 66035 26831 6407 donor10 -663.36 5e-324 26831 0.1071 0.0678 0.072 0.1749 0.7527 0.0004 0 0.0141823125252599 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn2 ACATCCCCACTCAAGT gabaergic 1.0 False donor17 65382 26619 6149 donor17 -578.38 5e-324 26619 0.1055 0.0868 0.0706 0.1923 0.734 0.0031 0 0.013270563813619 Pittsburgh 67.0 Male Black or African-American Not Hispanic or Latino 10.87 non-HBCAC archival +rxn2 GGAAGTGAGACAACTA glutamatergic 1.0 False donor9 64272 25957 6202 donor9 -496.17 5e-324 25957 0.1234 0.0826 0.0703 0.206 0.7219 0.0019 0 0.012854154782278 Maryland 43.0 Female White Not reported 18.0 non-HBCAC archival +rxn2 TATTGCTGTGGAGGTT gabaergic 1.0 False donor12 61557 25469 6780 donor12 -398.72 5e-324 25469 0.1752 0.1612 0.0585 0.3364 0.5899 0.0151 0 0.0129442312909351 Pittsburgh 41.0 Female White Not Hispanic or Latino 26.12 non-HBCAC archival +rxn2 ATTCGTTCACTGAGTT glutamatergic 1.0 False donor15 61744 25351 6454 donor15 -482.83 5e-324 25351 0.1094 0.0678 0.0731 0.1772 0.7482 0.0015 0 0.0162973885375034 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn2 TCATCCGCATTCTCCG glutamatergic 1.0 False donor9 58769 25104 5447 donor9 -445.76 5e-324 25104 0.1135 0.0648 0.0664 0.1783 0.751 0.0043 0 0.0175328741390106 Maryland 43.0 Female White Not reported 18.0 non-HBCAC archival +rxn2 TCTGCCAGTCCAAAGG gabaergic 1.0 False donor10 62386 25070 5721 donor10 -572.92 5e-324 25070 0.0948 0.0564 0.0592 0.1512 0.7892 0.0004 0 0.0176717213275341 Pittsburgh 42.0 Female Black or African-American Not Hispanic or Latino 9.6 non-HBCAC archival +rxn2 TGTTACTAGGACAAGA glutamatergic 1.0 False donor5 59716 24892 6504 donor5 -506.88 5e-324 24892 0.1436 0.1345 0.0645 0.2781 0.6492 0.0082 0 0.0149194665400293 Maryland 28.0 Female Black or African-American Not_Hispanic_Latino 32.0 non-HBCAC archival +rxn2 AGTACCACATCCTCAC glutamatergic 1.0 False donor13 61400 24909 6134 donor13 -438.45 5e-324 24909 0.1144 0.0727 0.0663 0.1871 0.7451 0.0015 0 0.013817404386729 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn2 GTCTGTCTCAACGCTA glutamatergic 1.0 False donor13 60146 24815 6091 donor13 -430.61 5e-324 24815 0.1118 0.0604 0.0688 0.1722 0.7581 0.0009 0 0.0161757126432225 Pittsburgh 53.0 Male White Not Hispanic or Latino 21.63 non-HBCAC archival +rxn2 GTCTACCCACCAGCCA glutamatergic 1.0 False donor9 57071 24750 5586 donor9 -394.79 5e-324 24750 0.1082 0.0628 0.0718 0.171 0.7486 0.0086 0 0.0167646591450819 Maryland 43.0 Female White Not reported 18.0 non-HBCAC archival +rxn2 GGGCTACAGGTAAAGG glutamatergic 1.0 False donor15 59372 24553 5816 donor15 -441.66 5e-324 24553 0.1118 0.0694 0.0679 0.1812 0.7488 0.0021 0 0.0183904369727742 Pittsburgh 18.0 Female White Not Hispanic or Latino 27.95 non-HBCAC archival +rxn2 GGTGGCTAGGCAGTCA glutamatergic 1.0 False donor7 61557 24624 6316 donor7 -435.63 5e-324 24624 0.1096 0.0766 0.0727 0.1862 0.7396 0.0014 0 0.0124724283136154 Maryland 49.0 Female White Not reported 24.0 non-HBCAC archival +rxn2 ACGATCAGTAGAATAC glutamatergic 1.0 False donor17 59429 24479 6538 donor17 -476.51 5e-324 24479 0.1421 0.1058 0.0616 0.2479 0.6866 0.0038 0 0.0134209253586974 Pittsburgh 67.0 Male Black or African-American Not Hispanic or Latino 10.87 non-HBCAC archival +rxn2 CGAGTTATCGTCTCAC gabaergic 1.0 False donor19 59729 24285 5640 donor19 -488.16 5e-324 24285 0.1051 0.0764 0.0646 0.1814 0.7491 0.0048 0 0.021081909061593 Pittsburgh 27.0 Male White Not Hispanic or Latino 14.52 non-HBCAC archival +rxn2 ATACTTCAGAATTTGG gabaergic 1.0 False donor8 57326 24457 5632 donor8 -518.89 5e-324 24457 0.0994 0.0617 0.0554 0.1611 0.7823 0.0012 0 0.0132736222060841 Maryland 32.0 Male Black or African-American Not reported 23.0 non-HBCAC archival +rxn2 GATGCTAAGACTTCGT glutamatergic 1.0 False donor4 59911 24431 6522 donor4 -446.86 5e-324 24431 0.1132 0.0783 0.0891 0.1915 0.7162 0.0033 0 0.0124898949070331 Maryland 27.0 Male White Not_Hispanic_Latino 33.0 non-HBCAC archival