diff --git a/.changeset/gorgeous-nails-watch.md b/.changeset/gorgeous-nails-watch.md
new file mode 100644
index 000000000..0d0696f43
--- /dev/null
+++ b/.changeset/gorgeous-nails-watch.md
@@ -0,0 +1,5 @@
+---
+"@callstack/repack": minor
+---
+
+Enable inlining entry modules by making runtime initialization from React renderers a no-op
diff --git a/packages/repack/src/plugins/RepackTargetPlugin/RepackTargetPlugin.ts b/packages/repack/src/plugins/RepackTargetPlugin/RepackTargetPlugin.ts
index 8ce0ffe5b..f2d2a0ee0 100644
--- a/packages/repack/src/plugins/RepackTargetPlugin/RepackTargetPlugin.ts
+++ b/packages/repack/src/plugins/RepackTargetPlugin/RepackTargetPlugin.ts
@@ -92,6 +92,14 @@ export class RepackTargetPlugin implements RspackPluginInstance {
       }
     ).apply(compiler);
 
+    // ReactNativePrivateInitializeCore.js is an unnecessary module exisiting in order to make metro happy
+    // it reexports InitializeCore which is included as one of the initial modules running before main entrypoint
+    // making this module noop makes inlining entry modules possible which might improve startup time
+    new compiler.webpack.NormalModuleReplacementPlugin(
+      /react-native.*?([/\\]+)Libraries[/\\]ReactPrivate[/\\]ReactNativePrivateInitializeCore\.js$/,
+      require.resolve('../../modules/EmptyModule.js')
+    ).apply(compiler);
+
     // ReactNativeTypes.js is flow type only module
     new compiler.webpack.NormalModuleReplacementPlugin(
       /react-native.*?([/\\]+)Libraries[/\\]Renderer[/\\]shims[/\\]ReactNativeTypes\.js$/,