PTN000301499 DNA replication

[ValWood]

• PTHR ID & PTN node:

GO:0006260 | DNA replication | IBA with O60870 , MGI:96676 , PTN000301499

• Sequences with problematic annotation (ID + gene/protein name):

https://www.pombase.org/gene/SPBC365.09c
(but all)

• Type of Issue: Erroneous source or erroneous propagation, or other issue

Annotation:

The human DNA replication is from this paper. This seems very weak (and very old)
https://pubmed.ncbi.nlm.nih.gov/12359749/

The UniProt description says
Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo (By similarity).
Binds via its C-terminal domain to RNA in vitro

The mouse DNA replication is from another old paper from the same authors
https://pubmed.ncbi.nlm.nih.gov/8954809/ (1996)
this is the abstract. I don't see how anyone gets DNA replication from this? There is no mention of DNA replication in the paper
We report the isolation of the mouse Kin17 gene, located on chromosome 2, coding a nuclear Zn-finger protein that has a 39-residue region homologous to Escherichia coli RecA protein and that is recognized by anti-RecA antibodies. Kin17 protein preferentially binds to curved DNA in vitro and in vivo, suggesting a role in illegitimate recombination and in regulation of gene expression. We have shown that the Kin17 gene is about 8 kb in length and displays three exons and two introns. The 5' flanking region lacks a canonical TATAA box but presents several putative regulatory domains. A major transcription initiation site is located 322 nucleotides upstream of the translation start site. The 1.7-kb transcript of the Kin17 gene is weakly and ubiquitously expressed in murine tissues and cell lines as determined by Northern analysis. The cross-hybridization of Kin17 cDNA with the genomic DNA of other species in Southern analysis indicates the conservation of the gene among mammals and suggests that the Kin17 gene plays a conserved role in DNA metabolism.

• Add the label 'high priority' if needed. Generally high priority issues affect a lot of proteins, and annotations are incorrect (as opposed to just imprecise).

Personally I think both papers should be flagged as not for GO annotation, the role is inconclusive