diff --git a/src/ontology/go-edit.obo b/src/ontology/go-edit.obo index 6f7133e96..7357e61da 100644 --- a/src/ontology/go-edit.obo +++ b/src/ontology/go-edit.obo @@ -15438,7 +15438,7 @@ namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:0000150 ! glandular secretory epithelial cell +intersection_of: results_in_acquisition_of_features_of CL:0000150 ! glandular epithelial cell [Term] id: GO:0002068 @@ -15447,7 +15447,7 @@ namespace: biological_process def: "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0032502 ! developmental process -intersection_of: results_in_development_of CL:0000150 ! glandular secretory epithelial cell +intersection_of: results_in_development_of CL:0000150 ! glandular epithelial cell relationship: part_of GO:0002067 ! glandular epithelial cell differentiation [Term] @@ -15477,7 +15477,7 @@ namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation -intersection_of: results_in_maturation_of CL:0000150 ! glandular secretory epithelial cell +intersection_of: results_in_maturation_of CL:0000150 ! glandular epithelial cell relationship: part_of GO:0002068 ! glandular epithelial cell development [Term] @@ -32411,8 +32411,10 @@ synonym: "RNA nucleotidyltransferase (DNA-directed) activity" RELATED [EC:2.7.7. synonym: "RNA polymerase I activity" NARROW [EC:2.7.7.6] synonym: "RNA polymerase II activity" NARROW [EC:2.7.7.6] synonym: "RNA polymerase III activity" NARROW [EC:2.7.7.6] +synonym: "RNA polymerase IV activity" NARROW [] +synonym: "RNA polymerase V activity" NARROW [] synonym: "transcriptase" BROAD [EC:2.7.7.6] -xref: EC:2.7.7.6 +xref: EC:2.7.7.6 {source="skos:exactMatch"} xref: MetaCyc:DNA-DIRECTED-RNA-POLYMERASE-RXN is_a: GO:0034062 ! 5'-3' RNA polymerase activity relationship: part_of GO:0032774 ! RNA biosynthetic process @@ -200698,19 +200700,7 @@ id: GO:0034062 name: 5'-3' RNA polymerase activity namespace: molecular_function def: "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end." [GOC:mah, GOC:pf, RHEA:21248] -synonym: "C ribonucleic acid formation factors" RELATED [EC:2.7.7.6] -synonym: "C RNA formation factors" RELATED [EC:2.7.7.6] -synonym: "ribonucleate nucleotidyltransferase activity" RELATED [EC:2.7.7.6] -synonym: "ribonucleate polymerase activity" RELATED [EC:2.7.7.6] -synonym: "ribonucleic acid nucleotidyltransferase" BROAD [EC:2.7.7.6] -synonym: "ribonucleic acid polymerase activity" RELATED [EC:2.7.7.6] -synonym: "ribonucleic acid transcriptase activity" RELATED [EC:2.7.7.6] -synonym: "ribonucleic polymerase activity" RELATED [EC:2.7.7.6] -synonym: "ribonucleic transcriptase activity" RELATED [EC:2.7.7.6] -synonym: "RNA nucleotidyltransferase activity" RELATED [EC:2.7.7.6] synonym: "RNA polymerase activity" BROAD [] -synonym: "RNA transcriptase activity" RELATED [EC:2.7.7.6] -synonym: "transcriptase" BROAD [EC:2.7.7.6] xref: RHEA:21248 {source="skos:exactMatch"} is_a: GO:0097747 ! RNA polymerase activity property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/28776" xsd:anyURI @@ -233248,7 +233238,7 @@ def: "Binding to interleukin-16." [GOC:jl] synonym: "IL-16 binding" EXACT [] is_a: GO:0019955 ! cytokine binding intersection_of: GO:0005488 ! binding -intersection_of: has_primary_input PR:000001374 ! pro-interleukin-16 +intersection_of: has_primary_input PR:000001374 ! interleukin-16 [Term] id: GO:0042012 @@ -233259,7 +233249,7 @@ synonym: "IL-16 receptor activity" EXACT [GOC:mah] synonym: "IL-16R" EXACT [] is_a: GO:0004896 ! cytokine receptor activity intersection_of: GO:0038023 ! signaling receptor activity -intersection_of: has_primary_input PR:000001374 ! pro-interleukin-16 +intersection_of: has_primary_input PR:000001374 ! interleukin-16 relationship: has_part GO:0042011 ! interleukin-16 binding [Term] @@ -353925,7 +353915,7 @@ def: "The process in which a relatively unspecialized cell acquires specialized is_a: GO:0060487 ! lung epithelial cell differentiation is_a: GO:0061101 ! neuroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:1000223 ! pulmonary neuroendocrine cell +intersection_of: results_in_acquisition_of_features_of CL:1000223 ! lung neuroendocrine cell created_by: dph creation_date: 2010-04-27T03:28:46Z @@ -354357,7 +354347,7 @@ namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells." [GOC:cilia, GOC:dph, GOC:krc] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:1000271 ! lung multiciliated epithelial cell +intersection_of: results_in_acquisition_of_features_of CL:1000271 ! lung ciliated cell created_by: dph creation_date: 2010-05-25T09:31:14Z @@ -464957,7 +464947,7 @@ namespace: cellular_component def: "A dense cluster of elongated, thick microvilli on the apical surface of tuft cells in epithelial tissues, such as the intestine and respiratory tract. The apical tuft extends further into the lumen than typical microvilli, featuring larger, more compact projections with unique actin cores that penetrate deep into the cytoplasm, often reaching the perinuclear region. This distinctive structure, rich in microfilaments and microtubules, supports the chemosensory functions of the cell." [PMID:15817800, PMID:35237268] is_a: GO:0098862 ! cluster of actin-based cell projections relationship: has_part GO:0005902 ! microvillus -relationship: part_of CL:0002204 ! brush cell +relationship: part_of CL:0002204 created_by: ce creation_date: 2024-11-14T11:13:07Z @@ -524878,7 +524868,7 @@ namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell." [GO_REF:0000086, GOC:sp, GOC:TermGenie, PMID:22231168, PMID:24934224] synonym: "multiciliate cell differentiation" BROAD [] intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:0005012 ! multiciliated epithelial cell +intersection_of: results_in_acquisition_of_features_of CL:0005012 ! multi-ciliated epithelial cell created_by: tb creation_date: 2014-08-05T19:21:21Z @@ -532743,7 +532733,7 @@ namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland." [GO_REF:0000086, GOC:TermGenie, PMID:17018284, PMID:18334552, PMID:19944183] synonym: "sebocyte differentiation" EXACT [CL:0002140] intersection_of: GO:0030154 ! cell differentiation -intersection_of: results_in_acquisition_of_features_of CL:0002140 ! skin sebocyte +intersection_of: results_in_acquisition_of_features_of CL:0002140 ! acinar cell of sebaceous gland created_by: cls creation_date: 2014-11-30T11:51:57Z @@ -582199,7 +582189,7 @@ def: "The multiplication or reproduction of sebocytes by cell division, resultin synonym: "sebocyte proliferation" RELATED [GOC:dph] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation -intersection_of: acts_on_population_of CL:0000317 ! sebocyte +intersection_of: acts_on_population_of CL:0000317 ! sebum secreting cell created_by: hjd creation_date: 2015-02-23T19:43:49Z