LyRic is a versatile automated transcriptome annotation and analysis workflow written in the Snakemake language. Its core functionality is the production of:
- a set of high-quality RNA Transcript Models (TMs) mapped onto a genome sequence, based on Long-Read (LR) RNA sequencing data.
- various summary statistics plots and analysis results that describe the input and output data in details
- an interactive HTML table reporting statistics for each input sample, enabling easy and intuitive sample-to-sample comparison
- a UCSC Track Hub to display output TMs, as well as various other tracks produced by LyRic.
(Note that features 2, 3 and 4 can be easily switched on and off).
LyRic is platform-agnostic, i.e. it can deal with FASTQ data coming from both the ONT and PacBio platforms.
Full LyRic documentation is here.