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<html>
<html lang="en">
<head>
<meta charset="utf-8">
<title>
Main Page- Computational Str.Bio
</title>
<link rel="stylesheet" type="text/css" href="comp.css">
</head>
<body>
<h1>
<pre>
###------------------------------------------------###
# COMPUTATIONAL STRUCTURAL BIOLOGY : AN INTRODUCTION #
###------------------------------------------------###
</pre>
</h1>
<div class="topnav">
<a href="./Index.html">Home</a>
<a href="https://www.nwoodweb.xyz/ENCPortfolioWeb/Visualization.html">Visualizing Biomolecules </a>
<a href="https://www.nwoodweb.xyz/ENCPortfolioWeb/MolDynamics.html"> Modeling Complex Interactions </a>
<a href="https://www.nwoodweb.xyz/ENCPortfolioWeb/QuantumMechanics.html"> Quantifying Quantum Mechanics </a>
</div>
<h2>
<pre>
*************************
* COMPUTERS FOR BIOLOGY *
*************************
</pre>
<img src="./GRAPHICS/keratin.png" style="float:right;width:200px;height:400px;">
</h2>
<p> ~ Scientists are constantly unearthing increasing amounts of biological data, leading to the problem of not only storing and sharing this data in a universally accessible manner, but also using this data in a meaningful manner </p>
<p>This has lead to the advent of free to use databases such as the <a href="https://www.ncbi.nlm.nih.gov/">NCBI</a> and <a href="https://www.uniprot.org/">UNIPROT</a> , which catalogue a litany of biological data</p>
<img src="./GRAPHICS/Cuda.png" style="float:right;width:300px;height:150px;" alt="NVIDIA CUDA is a hardware acceleration platform">
<p>~ In order to solve increasingly complex biological problems, scientists and doctors make use of High Performance Computing<a href="https://insidehpc.com/hpc-basic-training/what-is-hpc/">(HPC)</a> and hardware acceleration to expedite the process of solving, or in many cases, approximating, these biological problems </p>
<h2><pre>
**************************
* MATHEMATICS IN BIOLOGY *
**************************
</pre></h2>
<p>~ We use mathematics to make quantifiable sense of our surroundings </p>
<p>~ Mathematics in biology addresses a variety of problems, including biostatistics and public health, chemical bonding, diffusion in the cell, population dynamics, and predator-prey relationships </p>
<p>~ Some of these biological and chemical observations are stochastic, meaning that many of the variables can vary drastically, or in many cases such as the weather, be completely random </p>
<center>
<figure>
<img src="./hiv.png"
style="float:center;width:300px;height:300px;"
alt="HIV-1 Virus Capsid Protein"/>
<figcaption style="color:#ffb000;font-size:18px;">Capsid (outer shell) of HIV-1 <a href="https://www.rcsb.org/structure/3j3q">(3J3Q)</a>, rendered in PyMOL. Note the lobsided shape, which challenges the assumption that nature favors symmetry</figcaption>
</figure>
</center>
<span style="background-color: #ffb000;color: black;font-size:20px">(END)</span>
<p>
</p>
</body>
</html>