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obsolete.owl
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<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/obi/dev/modules/obsolete.owl#"
xml:base="http://purl.obolibrary.org/obo/obi/dev/modules/obsolete.owl"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#">
<owl:Ontology rdf:about="http://purl.obolibrary.org/obo/obi/dev/modules/obsolete.owl"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/IAO_0000112 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000112"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000114 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000114"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000115 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000117 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000118 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000118"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000119 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000231 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000231"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000232 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000232"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000233 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000233"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000234 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000234"/>
<!-- http://purl.obolibrary.org/obo/IAO_0100001 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0100001"/>
<!-- http://purl.obolibrary.org/obo/OBI_9991118 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/OBI_9991118"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/OBI_0000050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000050">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A platform is an object_aggregate that is the set of instruments and software needed to perform a process. definition_source: OBI.</obo:IAO_0000115>
<obo:IAO_0000117>OBI Instrument branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI Instrument branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_platform</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000100 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000100">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Rat 1A; first enrolled patient to receive treatment</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">First subject treated role is a study subject role borne by the subject realized in the application of the process specified in intervention study design with no previous study subject realizing the role prior in the study</obo:IAO_0000115>
<obo:IAO_0000117>Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_role of being first subject treated</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000109 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000109">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>1983 Sci. Amer. Jan. 58/2 Plasmids are routinely used as vectors for introducing foreign DNA into bacteria.</obo:IAO_0000112>
<obo:IAO_0000112>Some epidemiological aspects and vector role of tick infestation on layers in the Faisalabad district (Pakistan). http://journals.cambridge.org/action/displayAbstract;jsessionid=0373164489D00868AEEF2C556EB4FD29.tomcat1?fromPage=online&aid=624280</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a biological vector role is a material to be added role that is realized by the process of transmitting material to the organism that is the target of the transmission.</obo:IAO_0000115>
<obo:IAO_0000117>GROUP: Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI and Wikipedia</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete biological vector role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000140 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000140">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">Label role is a role which inheres in a material entity and which is realized in a detection of label assay</obo:IAO_0000115>
<obo:IAO_0000117>Role Branch</obo:IAO_0000117>
<obo:IAO_0000118>label</obo:IAO_0000118>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0002743"/>
<rdfs:label>obsolete_label role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000205 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000205">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Escaped rat; human who moved to another city. Rat which escapes part way through a study; a human study participant who moved to another city before the study was completed (and stopped participating in the study)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Dropout is a study subject role borne by an entity realized by a process of leaving the study earlier than the protocol specified and where the bearer of the dropout role had been borne study subject role prior to bearing dropout role.</obo:IAO_0000115>
<obo:IAO_0000117>Role Branch</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_dropout role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000207 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000207">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a worker role of providing medical care either within or outside the study timeline</obo:IAO_0000115>
<obo:IAO_0000117>Person:Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000118>health care provider</obo:IAO_0000118>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OMRSE_00000012"/>
<rdfs:label>obsolete health care provider role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000223 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000223">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>115 patients received ipilimumab and blinded medication</obo:IAO_0000112>
<obo:IAO_0000112>Inert pill shaped like aspirin tablet</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Is a role which inheres in a material entity which is manufactured to be similar in appearance to a test material entity in e.g. a clinical trial to prevent participants from detecting which is the active and inactive substance</obo:IAO_0000115>
<obo:IAO_0000117>Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_blinded medication role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000233 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000233">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">Place holder class, Utility class to gather the defined classes</obo:IAO_0000115>
<obo:IAO_0000117>Susanna Sansone</obo:IAO_0000117>
<obo:IAO_0000119>OBI Biomaterial derived</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
<rdfs:label>obsolete_defined_material</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000264 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000264">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand. Drug Alcohol Rev. 2008 Mar 31:1-7. PMID: 18608458</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A sample population is an object aggregate that is selected from the population, e.g. the fish in the net that were sampled from the lake, the people that responded to the call for volunteers.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Jennifer Fostel</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000118>recruited population</obo:IAO_0000118>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<rdfs:label>obsolete_sample population</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000296 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000296">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Enrollment of patients in a study. Short-term outcome of neuropsychiatric events in systemic lupus erythematosus upon enrollment into an international inception cohort study. Arthritis Rheum. 2008 May 15;59(5):721-9. PMID: 18438902</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">enrollment is a process of identifying a set of objects for further use in an investigation based on a set of criteria or rules</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<rdfs:label>obsolete_enrollment</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000323 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000323">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000115 xml:lang="en">is the serous membrane that forms the lining of the abdominal cavity</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_peritoneum</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000340 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000340">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Recording the current temperature in a laboratory notebook. Writing a journal article. Updating a patient record in a database.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>wikipedia http://en.wikipedia.org/wiki/Documenting</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000572"/>
<rdfs:label>obsolete_documenting</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000420 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000420">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>A trypsinized suspension of cells</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000115 xml:lang="en">A material entity that has undergone a process of digestion with trypsin</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_trypsinized material</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000442 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000442">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Alan Ruttenberg's heart</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000115 xml:lang="en">The heart is a muscular organ found in all vertebrates that is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Heart</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000230"/>
<rdfs:label>obsolete_heart</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000446 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000446">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>DNA cleavage assay for the identification of topoisomerase I inhibitors. Nat Protoc. 2008;3(11):1736-50. PMID: 18927559</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000124"/>
<obo:IAO_0000115 xml:lang="en">a process by which the identity (what a thing is) of a material entity is established within a certain confidence interval</obo:IAO_0000115>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_identification</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000449 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000449">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>example of subclass: normalized data set - A normalized data set is a data set that is produced as the output of a normalization data transformation.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">This is only a placeholder for defined classes, as are its siblings _defined_material and _defined protocol application. Its children should be defined classes constructed as output of a process.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: James Malone</obo:IAO_0000117>
<obo:IAO_0000117>PERSON: Melanie Courtot</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000226"/>
<rdfs:label>obsolete_defined_output</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000577 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000577">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>the phosphate concentration should be 0.1M</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A concentration is a relational quality that inheres in a material entity towards molecular scattered aggregate that is part of it by virtue of some ratio of masses of the two or the counts of the grains of the two or volume occupied by the larger material entity.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000119>Discussion in Karslruhe, Oct 2008, with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg.</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_molecular concentration</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000665 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000665">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Permeabilizing T cells and staining them with fluorescent labeled anti-IFN-gamma antibodies</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">The measurement of cytokines within the cytoplasm of a cell by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>ICCS</obo:IAO_0000118>
<obo:IAO_0000118>ICS</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<obo:OBI_9991118>intracellular cytokine staining (ICS)</obo:OBI_9991118>
<rdfs:label>obsolete intracellular cytokine staining assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000667 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000667">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Measuring T cells that are specific for the SYFPEITHI peptide when presented by the murine MHC molecule H-2 Kd by staining them with a tetramer of peptide loaded MHC complexes.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An MHC multimer assay is an assay that detects T cells capable of binding the MHC:ligand complexes present in the multimer. The multimer is fluorescently labelled. The T cells bound to multimers are counted in a flow cytometer</obo:IAO_0000115>
<obo:IAO_0000117>IEDB</obo:IAO_0000117>
<obo:IAO_0000118>MHC tetramer assay</obo:IAO_0000118>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_1110179"/>
<obo:OBI_9991118>MHC tetramer/multimer staining</obo:OBI_9991118>
<rdfs:label>obsolete MHC multimer staining assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000682 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000682">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">Study result is an information content entity that is a specified data output of a study.</obo:IAO_0000115>
<obo:IAO_0000119>GROUP: OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000230"/>
<rdfs:label>obsolete_study result</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000698 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000698">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A DNA ligase is an enzyme that covalently joins two compatible pieces of DNA through the cleavage of an ATP molecule</obo:IAO_0000115>
<obo:IAO_0000117>Kevin Clancy, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000118>ligase</obo:IAO_0000118>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_DNA ligase</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000794 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000794">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000002"/>
<obo:IAO_0000119>SO:0000235</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0000232>PLace_holder for sequence ontology term</obo:IAO_0000232>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1553</obo:IAO_0000233>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/SO_0000235"/>
<rdfs:label>obsolete transcription factor binding site</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000797 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000797">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>SIINFEKL' is the primary structure of a peptide</obo:IAO_0000112>
<obo:IAO_0000115 xml:lang="en">The primary structure of a protein that is completely defined by the set of its amino acid residue parts and the linear order induced by the peptide bonds that hold them together</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_primary structure of protein</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000830 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000830">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000115 xml:lang="en">A quality inhering in a molecule that is completely defined by the linear sequence of a set of residues which are connected by directional, linear bonds</obo:IAO_0000115>
<obo:IAO_0000117>Person:Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_primary structure of sequence macromolecule</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000844 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000844">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>human ethics approval was obtained from the Southern Tasmania Health & Medical Human Research Ethics Committee and the Royal Hobart Hospital Research Ethics Committee [pmid:19696660]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A medical organization at which sick or injured people are given clinical care</obo:IAO_0000115>
<obo:IAO_0000117>Person:Alan Ruttenberg</obo:IAO_0000117>
<obo:IAO_0000117>Person:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>modified from the wording of the wordnet definition; http://www.golovchenko.org/cgi-bin/wnsearch?q=hospital#2n</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/1295</obo:IAO_0000233>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OMRSE_00000056"/>
<rdfs:label>obsolete hospital</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000851 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000851">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_diethyl pyrocarbonate</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000856 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000856">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">An assay in which the presence of a material inside a cell is measured by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<obo:OBI_9991118>intracellular staining</obo:OBI_9991118>
<rdfs:label>obsolete intracellular material detection by flow cytometry assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000926 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000926">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_ambidexterious handedness</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000929 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000929">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>EBI provides training on databases and tools and has a training service provider role</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a service provider role which is realized by a servicer provider organization performing some training</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_training service provider role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000936 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000936">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>A person or organization who provides access to a DNA sequencer.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">a service provider role which is realized by a servicer provider organization performing access to some material</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000119>OBI</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_material access provider role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000937 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000937">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_left handedness</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000956 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000956">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/PATO_0002201"/>
<rdfs:label>obsolete_handedness</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000972 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000972">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000115 xml:lang="en">a processed material created to have a function and which requires electrical power to execute</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_electrically powered device</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000974 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000974">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_right handedness</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000980 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000980">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>DNA sequencing of a sample by a core lab which returns data to the consumer</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a service provider role which is realized by a servicer provider organization performing a protocol execution</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Helen Parkinson</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_protocol service provider role</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000986 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000986">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A training process with the objective to provide a trainee with the skill to run DNA sequencing experiments</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_DNA sequencing training service</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000987 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000987">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000124"/>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_general scalar measurement datum</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0000988 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0000988">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Diagnosing that a patient has pneumonia based on information on measurements of temperature, sound of breathing, and patient complaining about a headache.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">The interpretation of the information available about bodily features (clinical picture) of a patient resulting in a diagnosis</obo:IAO_0000115>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<obo:IAO_0000233>https://github.com/obi-ontology/obi/issues/623</obo:IAO_0000233>
<rdfs:label>obsolete performing a diagnosis</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001009">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A binding assay where the specified output determines if two or more material entities do or do not have the disposition to form a complex above a threshold level of significance. The threshold can be defined through detection limits of the instrument, the use of experimental controls that establish what is considered significant binding, or a predefined cutoff based on what binding is considered significant in a certain context.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters, Randi Vita, Jason Greenbaum</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_qualitative binding detection assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001037 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001037">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A specimen fixation function is a function that holds or fastens an entity in a fixed position.</obo:IAO_0000115>
<obo:IAO_0000117>EAGLE-I</obo:IAO_0000117>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<rdfs:label>obsolete_specimen fixation function</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001250 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001250">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">An intracellular material detection by flow cytometry assay that measures epitope specific cytotoxic T cell degranulation</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0000916"/>
<obo:OBI_9991118>T cell degranulation by intracellular staining</obo:OBI_9991118>
<rdfs:label>obsolete intracellular material detection by flow cytometry assay of epitope specific cytotoxic T cell degranulation</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001540 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001540">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Using proliferation of a T cell line specific for SIINFEKL in response to material eluted from a cell as evidence that SIINFEKL was presented by MHC on that cell.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that identifies an MHC ligand using a T cell response assay as a readout</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Randi Vita, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0001469"/>
<obo:OBI_9991118>T cell recognition</obo:OBI_9991118>
<rdfs:label>obsolete T cell recognition of eluted MHC ligand assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001560 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001560">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the affinity of a ligand to a MHC in a cell lysate preparation and that quantifies the affinity with a binding constant.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete cell lysate MHC binding constant determination assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001572 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001572">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the affinity of a ligand to MHC moleculs bound to the cell surface and that quantifies the affinity with a binding constant.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete cell bound MHC binding constant determination assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001574 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001574">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">competitive inhibition of binding assay measuring MHC ligand binding by radioactivity detection using MHC derived from a cell lysate</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0001544"/>
<obo:OBI_9991118>cell lysate MHC competitive binding using radioactivity</obo:OBI_9991118>
<rdfs:label>obsolete cell lysate MHC competitive binding assay using radioactivity detection</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001576 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001576">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">An assay that measures the affinity of a ligand to a purified MHC complex preparation and that quantifies the affinity with a binding constant.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete purified MHC binding constant determination assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001582 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001582">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">direct binding assay measuring MHC ligand binding using MHC derived from a cell</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<obo:OBI_9991118>cell bound MHC direct binding</obo:OBI_9991118>
<rdfs:label>obsolete cell bound MHC direct binding assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001611 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001611">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">direct binding assay measuring MHC ligand binding using MHC derived from a purified MHC molecule preparation</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<obo:OBI_9991118>purified MHC direct binding</obo:OBI_9991118>
<rdfs:label>obsolete purified MHC direct binding assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001712 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001712">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A direct binding assay using a assay</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<obo:OBI_9991118>direct binding assay</obo:OBI_9991118>
<rdfs:label>obsolete B cell epitope direct binding assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001715 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001715">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A competitive inhibition of binding assay using a assay</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<obo:OBI_9991118>competitive binding assay</obo:OBI_9991118>
<rdfs:label>obsolete B cell epitope competitive binding assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0001737 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0001737">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000122"/>
<obo:IAO_0000115 xml:lang="en">A X-ray crystallography assay measuring epitope specfic antibody binding event in angstroms</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>IEDB (QTT)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_0001738"/>
<obo:OBI_9991118>X-ray crystallography [Ã…]</obo:OBI_9991118>
<rdfs:label>obsolete B cell epitope specific X-ray crystallography assay</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0002782 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0002782">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000115 xml:lang="en">A specimen that is derived from the upper respiratory tract</obo:IAO_0000115>
<obo:IAO_0000117>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000117>
<obo:IAO_0000119>Asiyah Yu Lin ORCID:0000-0003-2620-0345</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000227"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/OBI_2000006"/>
<rdfs:label>obsolete_upper respiratory specimen</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100015 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100015">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>Tissue, organ, system, sperm, blood or body location (arm).</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000121"/>
<obo:IAO_0000115 xml:lang="en">An anatomical entity is a material entity that is part of a multicellular organism, and which is large enough so that it forms an identifiable structure in the organism. Specifically, it excludes granular parts of the organism, such as atoms, molecules, cells, which can be removed from the organism without affecting it. It is defined as the union of 'multi-tissue structure', 'body substance' and 'portion of tissue'</obo:IAO_0000115>
<obo:IAO_0000117>Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000117>Philippe Rocca-Serra</obo:IAO_0000117>
<obo:IAO_0000117>Tina Boussard</obo:IAO_0000117>
<obo:IAO_0000119>MO</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_anatomical entity</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100035">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>a single Hela cell</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">a cell derived from a multicellular organism that has the potential to replicate indefinitely</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_immortal cell</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100039 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100039">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>the peptide with sequence SIINFEKL, which is eluted from a cell expressing hen egg lysozyme</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000123"/>
<obo:IAO_0000115 xml:lang="en">A material entity which is derived from a protein</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Bjoern Peters</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: IEDB</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000103"/>
<rdfs:label>obsolete_fragment derived from protein</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100055">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A material entity that represents generations of a primary culture.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON: Susanna Sansone</obo:IAO_0000117>
<obo:IAO_0000119>GROUP: OBI Biomaterial Branch</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<rdfs:label>obsolete_cell line cell</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100056">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A cell line that is expected to be capable of indefinite propagation in an vitro culture.</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>immortal cell line sample</obo:IAO_0000118>
<obo:IAO_0000118>permanent cell line</obo:IAO_0000118>
<obo:IAO_0000119>PERSON:Matthew Brush</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/CLO_0009828"/>
<rdfs:label>obsolete_immortal cell line culture</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/OBI_0100062 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/OBI_0100062">
<rdfs:subClassOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#ObsoleteClass"/>
<obo:IAO_0000112>A split of HeLa cells in active culture, or stored in frozen aliquots. Populations of HEK 293 cells used in experiments such as those documented in Changes in ultrastructure and endogenous ionic channels activity during culture of HEK 293 cell line. Eur J Pharmacol. 2007 Jul 12;567(1-2):10-8. PMID: 17482592.</obo:IAO_0000112>
<obo:IAO_0000112>He, Tong-Chuan, et al. Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512. - To evaluate the transcriptional effects of APC, we studied a human colorectal cancer cell line (HT29-APC) containing a zinc-inducible APC gene and a control cell line (HT29–β-Gal) containing an analogous inducible lacZ gene. Note that common usage in the literature is often of the form a human colorectal cancer cell line, as seen above. But such references to studies in a line refer to the fact that discrete populations of cells that are input into culturing or experiments, not an entire lineage of cells. It is these discrete populations that we refer to as 'cell lines'.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000120"/>
<obo:IAO_0000115 xml:lang="en">A secondary cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (ie has been successively passaged together in culture).</obo:IAO_0000115>
<obo:IAO_0000117>PERSON:Matthew Brush</obo:IAO_0000117>
<obo:IAO_0000118>cell line sample</obo:IAO_0000118>
<obo:IAO_0000119>OBI-CLO Alignment Working Group (Spring 2013)</obo:IAO_0000119>
<obo:IAO_0000231 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000228"/>
<obo:IAO_0100001 rdf:resource="http://purl.obolibrary.org/obo/CLO_0000031"/>
<rdfs:label>obsolete_cell line</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:Class>