diff --git a/docs/reference/phenotype-data.md b/docs/reference/phenotype-data.md index 8bd35340..5b341f6b 100644 --- a/docs/reference/phenotype-data.md +++ b/docs/reference/phenotype-data.md @@ -97,7 +97,7 @@ Pre-coordinated phenotype data is popular in the clinical domain, where a lot of ![Phenopacket](../images/phenopacket.png) -Apart from clinical diagnostics, pre-coordinated phenotype terms are used in many other contexts such as model organism research (e.g. [IMPC](https://www.mousephenotype.org/)) or the curation of [Genome Wide Association Studies](https://www.ebi.ac.uk/gwas/). For example, the GWAS Catalog can be browsed by the pre-coordinated term ["cardiac hypertrophy" (enlarged heart)](https://www.ebi.ac.uk/gwas/efotraits/EFO_0002503) to find gene assocations with the phenotype. +Apart from clinical diagnostics, pre-coordinated phenotype terms are used in many other contexts such as model organism research (e.g. [IMPC](https://www.mousephenotype.org/)) or the curation of [Genome Wide Association Studies](https://www.ebi.ac.uk/gwas/). For example, IMPC can be searched using the pre-coordinated term ["enlarged heart"](https://www.mousephenotype.org/data/phenotypes/MP:0000274) to find knockout mice with this phenotype, and similarly the GWAS Catalog can be browsed by the pre-coordinated term ["cardiac hypertrophy"](https://www.ebi.ac.uk/gwas/efotraits/EFO_0002503) to find gene assocations with the phenotype from GWAS studies. **Post-coordinated** phenotype curation simply means that the different constituents of phenotype (characteristic, bearer, modifier etc) are captured individually. This has certain advantages.