EgfrBoolean.txt

targets, factors
Egf, Egf
Egfr, Egf & ! Prkca
Shc1, Egfr
Grb2, Shc1 | Egfr | Jak1 | Jak2
Gab1, Egfr |  Grb2
Sos1, Grb2
Rasa1, Sos1 
Vav2, Egfr
Raf1, Rasa1
Rac1, Vav2 | Sos1
Cdc42, Vav2 | Sos1
Src, Shc1
Jak1, Egfr
Jak2, Egfr 
Stat1, Src | (Jak1 & Jak2) 
Stat3, Src | (Jak1 & Jak2)
Pik3r1, Egfr | Rasa1 | Gab1 | Jak1 | Jak2
Pdpk1, Pik3r1 | Mtorc2
Akt1, Pdpk1 | Mtorc2	
Foxo1, ! Akt1
Mdm2, Akt1 | Trp53
Trp53, ! Mdm2
Tsc2, !(Akt1 | Mapk1) | Gsk3b
Mtorc1, ! Tsc2 | Rasa1
Mtorc2, (! Rps6kb1 | ! Gsk3b) & ( Pik3r1 | Tsc2)
Eif4ebp1, ! Mtorc1
Eif4e, ! Eif4ebp1 | Mapk1
Ccnd1, ! Foxo1 | Eif4e | (Jun & Fos) | Myc
Cdk4, Ccnd1
Cdk6, Ccnd1
Plcg1, Egfr
diacylglycerol, Plcg1
Prkca, diacylglycerol
Nfkb1, Prkca & Gsk3b
Map2k1, (Raf1 & ! Prkca) | (Rac1 & Cdc42)
Mapk1, Map2k1
Bax, Trp53 
Casp3, Bax
Apoptosis, Casp3
Proliferation, Akt1 & !Gsk3b & Egf & Cdk4 & Cdk6 & Ccnd1 & ! Nfkb1 
Neurogenesis,   Cdk6 & ! Bax & Nfkb1 
Rps6kb1, Mtorc1 | Mapk1 | Jkamp
Mapkapk2, Mapk14
Rps6ka1, Mapk1 & Pdpk1
Mapk14, Mapk1 | Map2k1 | Map2k4 
Creb1, Rps6ka1 | Mapkapk2
Gsk3b, ! Rps6ka1 | ! Akt1
Myc, Mapk1 & ! Gsk3b
Map2k4, Rac1 & Cdc42
Map2k7, Rac1 & Cdc42
Jkamp, Map2k4 & Map2k7 
Jun, Jkamp
Fos, Jkamp | (Rps6ka1 & Mapk1)