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DESCRIPTION
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Package: RNAAgeCalc
Type: Package
Title: A multi-tissue transcriptional age calculator
Version: 1.1.2
Authors@R: c(
person("Xu", "Ren",
email = "[email protected]", role = c("aut", "cre")),
person("Pei Fen", "Kuan",
email = "[email protected]", role = "aut"))
Description: It has been shown that both DNA methylation and RNA transcription
are linked to chronological age and age related diseases. Several
estimators have been developed to predict human aging from DNA level and
RNA level. Most of the human transcriptional age predictor are based on
microarray data and limited to only a few tissues. To date, transcriptional
studies on aging using RNASeq data from different human tissues is limited.
The aim of this package is to provide a tool for across-tissue and
tissue-specific transcriptional age calculation based on GTEx RNASeq data.
License: GPL-2
URL: https://github.com/reese3928/RNAAgeCalc
BugReports: https://github.com/reese3928/RNAAgeCalc/issues
Encoding: UTF-8
Imports:
ggplot2,
recount,
impute,
AnnotationDbi,
org.Hs.eg.db,
stats,
SummarizedExperiment,
methods
Depends:
R (>= 3.6)
Suggests:
knitr,
rmarkdown,
testthat
RoxygenNote: 7.0.2
VignetteBuilder: knitr
biocViews: RNASeq,GeneExpression