Problem about process large amouts of data

[Losses]

I'm working around a neuroscience study, the goal is to calculate the WTC of brain signal between two people. The data includes 34552 points for each person.
While calculating the data on Windows, the program reported:

Error: cannot allocate vector of size 9.5 Gb

On CentOS, R was killed by OOM.

Is there any approach to finish the calculation?

[Gafre22]

I currently had this issue, all i did was to find more computing power. My University has this virtual computing network that allowed me to use more power to process wtc of 50k data points.