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Question - Fusion quadrupole isolation #18

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chhh opened this issue Jul 12, 2018 · 1 comment
Closed

Question - Fusion quadrupole isolation #18

chhh opened this issue Jul 12, 2018 · 1 comment

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@chhh
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chhh commented Jul 12, 2018

If I do an MS1 scan in orbi is the quadrupole used to filter out the ions that are outside the scan mass range?
Will the instrument behave differently if I do the following two scans:

["Analyzer" => "Orbitrap", "FirstMass" => 800, "LastMass" => 1000, "IsolationMode" => "None"]
["Analyzer" => "Orbitrap", "FirstMass" => 800, "LastMass" => 1000, "IsolationMode" => "Quadrupole"]
@chhh chhh changed the title Fusion - quadrupole isolation question Question - Fusion quadrupole isolation Jul 13, 2018
@dbaileychess
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When you specify 'Quadrupole' isolation, the quad will be switched to resolving mode and isolate the given mass range (FirstMass, LastMass). When the option is set to 'None', the quad is in RF-only mode and passes all masses through.

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@chhh @dbaileychess