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1. Enrich2 Enrich2 Public

   Tool for deep mutational scanning experiments.

   Python 45 12

2. Envision2017 Envision2017 Public

   We present Envision, an accurate predictor of protein variant molecular effect, trained using large-scale experimental mutagenesis data. All data and software in this study are freely available. Th…

   Jupyter Notebook 17 1

3. Enrich2-Example Enrich2-Example Public

   Example deep mutational scanning dataset for Enrich2

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4. VAMPseq VAMPseq Public

   We developed Variant Abundance by Massively Parallel Sequencing (VAMP-seq), which simultaneously measures the effects of thousands of missense variants on protein intracellular abundance, and appli…

   HTML 5 3

5. simdms simdms Public

   Deep mutational scanning dataset simulator.

   Python 3

6. 2017_GRAY_InformativeAA 2017_GRAY_InformativeAA Public

   To draw general conclusions about the effects of different amino acid substitutions, we analyzed 34,373 mutations in fourteen proteins whose effects were measured using large-scale mutagenesis appr…

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