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GMM_guassian_mixture_model_to_ATAC-SEQ

Using a GMM model to separate ATAC-seq reads in diferent nucleosome categories.

ATAC-seq data can present reads with diferent lenghts. This variance between the lenghts has different biological implications.

Given the lengh of all reads obtained in the ATAC-seq experiment, this model fits a gmm representing 4 types of nucleosome states:

  • Nucleosome free regions (<100 nucleotides)
  • MonoNucleosome (~ 200 nucleotides)
  • Diunucleosome (~ 400 nucleotides)
  • Trinucleosome (~ 600 nucleotides)

-This model receives as an input is a BAM aligment file.

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Using a GMM to separate reads from ATAC-seq experiment

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