Using a GMM model to separate ATAC-seq reads in diferent nucleosome categories.
ATAC-seq data can present reads with diferent lenghts. This variance between the lenghts has different biological implications.Given the lengh of all reads obtained in the ATAC-seq experiment, this model fits a gmm representing 4 types of nucleosome states:
- Nucleosome free regions (<100 nucleotides)
- MonoNucleosome (~ 200 nucleotides)
- Diunucleosome (~ 400 nucleotides)
- Trinucleosome (~ 600 nucleotides)
-This model receives as an input is a BAM aligment file.