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Fix spelling error
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SirDaev authored Oct 1, 2021
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Expand Up @@ -22,7 +22,7 @@ In a previous vignette you learned how to retrieve sequences from the NCBI datab

As mentioned previously, a subsection of the NCBI database called **RefSeq** consists of high quality DNA and protein sequence data. Furthermore, the NCBI entries for the RefSeq sequences have been **manually curated**, which means that expert biologists employed by NCBI have added additional information to the NCBI entries for those sequences, such as details of scientific papers that describe the sequences.

Another extremely important manually curated database is [UniProt](https://www.uniprot.org/) www.uniprot.org, which focuses on protein sequences. UniProt aims to contains manually curated information on all known protein sequences. While many of the protein sequences in UniProt are also present in RefSeq, the amount and quality of manually curated information in UniProt is much higher than that in RefSeq.
Another extremely important manually curated database is [UniProt](https://www.uniprot.org/) www.uniprot.org, which focuses on protein sequences. UniProt aims to contain manually curated information on all known protein sequences. While many of the protein sequences in UniProt are also present in RefSeq, the amount and quality of manually curated information in UniProt is much higher than that in RefSeq.

For each protein in UniProt, the UniProt curators read all the scientific papers that they can find about that protein, and add information from those papers to the protein’s UniProt entry. For example, for a human protein, the UniProt entry for the protein usually includes information about the biological function of the protein, in what human tissues it is expressed, whether it interacts with other human proteins, and much more. All this information has been manually gathered by the UniProt curators from scientific papers, and the papers in which the found the information are always listed in the UniProt entry for the protein.

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