Releases: kircherlab/cfDNA
Releases · kircherlab/cfDNA
v0.3.2
v0.3.1
v0.3.0
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updated documentation
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comfort:
- added geneIDs to WPS/COV/STARTs and FFT tables
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snakefile_GE_analysis:
- added background normalization
- ported FFT calculation to python
- separated multiple steps for increased maintainability
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snakefile_WPS:
- restructured file paths
- moved window extension to separate
- moved WPS padding correction to extractFromBAM_RegionBed_WPS_Cov.py
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GE_unsupervised:
- added rules for generating clusterings and heatmaps between all samples of an experiment using FFT intensities
- kmeans clustering
- HDBSCAN clustering
- heatmaps
- clustermaps (heatmap with hierarchical clustering)
- added rules for generating clusterings and heatmaps between all samples of an experiment using FFT intensities
v0.2.1
v0.2.0
refactor
- changed config.yml to example.config.yml
- updated schemas
- updated Documentation
new files
- updated blacklists for both genome builds
- updated genome files for both genome builds
new feature
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snakefile_GE_analysis:
- updated ProteinAtlas
- 3 types: Blood, Tissue, Tissue+cell-lines
- added support for GRCh38
- updated ProteinAtlas
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snakefile_WPS:
- added support for normalization by random background sequences
- generate random background sequences not overlapping target regions
- calculate WPS,COV,STARTS table for background sequences
- added support for normalization by random background sequences
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extractFromBAM_RegionBed_WPS_Cov.py
- added output for fragment endpoints (STARTS output)
- added strand specificity
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overlays.py:
- integrated normalization by background sequences