This is a clinico-genomic SMART on FHIR app which uses patient-specific genetic variants (SNPs) to assist care providers in selecting optimal medication regimens.
Built using Python and Flask web services, this app provides several unique services:
- SMART-standard web authentication.
- Conversion from VCF to appropriate FHIR resources to represent, store, and access variants in the EHR.
- VMC Allele Identifier generated and added for each variant's Observation resource.
- SNP-specific clinical annotations pulled from PharmGKB and stored in the Observation resources used to represent each variant.
- Formatting and visualization to simplify an otherwise complicated collection of recommendations.