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NTR mesenchymal lymphoid tissue organizer cell #2610

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13 changes: 13 additions & 0 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3100,6 +3100,7 @@ Declaration(Class(obo:CL_4047023))
Declaration(Class(obo:CL_4047025))
Declaration(Class(obo:CL_4047029))
Declaration(Class(obo:CL_4047030))
Declaration(Class(obo:CL_4047022))
Declaration(Class(obo:CL_4047032))
Declaration(Class(obo:CL_4047051))
Declaration(Class(obo:CL_4047052))
Expand Down Expand Up @@ -3155,6 +3156,7 @@ Declaration(Class(obo:GO_0042599))
Declaration(Class(obo:GO_0044316))
Declaration(Class(obo:GO_0046697))
Declaration(Class(obo:GO_0050893))
Declaration(Class(obo:GO_0051767))
Declaration(Class(obo:GO_0070278))
Declaration(Class(obo:GO_0070483))
Declaration(Class(obo:GO_0097729))
Expand Down Expand Up @@ -3206,6 +3208,7 @@ Declaration(Class(obo:PR_000012318))
Declaration(Class(obo:PR_000013015))
Declaration(Class(obo:PR_000013047))
Declaration(Class(obo:PR_000013433))
Declaration(Class(obo:PR_000013047))
Declaration(Class(obo:PR_000013502))
Declaration(Class(obo:PR_000014419))
Declaration(Class(obo:PR_000014898))
Expand Down Expand Up @@ -32871,6 +32874,16 @@ AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1038/s41467-022-33324-
AnnotationAssertion(rdfs:label obo:CL_4047030 "pre-venule capillary cell"@en)
SubClassOf(obo:CL_4047030 obo:CL_0002144)

# Class: obo:CL_4047022 (mesenchymal lymphoid tissue organizer cell)

AnnotationAssertion(Annotation(obo:IAO_0000115 "DOI:10.4049/jimmunol.1501724") Annotation(oboInOwl:hasDbXref "DOI:10.1038/s41586-021-03852-1") obo:IAO_0000115 obo:CL_4047022 "A stromal cell found in the adult gut that plays a crucial role in the formation and maintenance of gut-associated lymphoid tissues (GALTs). This cell is characterized by it's ability to interact with lymphoid tissue inducer (LTi) cells, express lymphotoxin beta receptor (LTβR) and vascular cell adhesion molecule (VCAM), produce chemokines and cytokines for immune cell recruitment and positioning, and contribute to the structural organization of lymphoid tissues within the intestinal environment. mLTo cells are distinguished from other stromal cells by their specific function in orchestrating the development and maintenance of organized lymphoid structures in the gut, which are essential for intestinal immune responses and homeostasis.")
AnnotationAssertion(terms:contributor obo:CL_4047022 <https://orcid.org/0009-0005-7919-4905>)
AnnotationAssertion(terms:date obo:CL_4047022 "2024-09-24T15:03:49Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1038/s41467-019-09728-3") oboInOwl:hasExactSynonym obo:CL_4047022 "mLTo cells")
AnnotationAssertion(rdfs:label obo:CL_4047022 "mesenchymal lymphoid tissue organizer cell"@en)
EquivalentClasses(obo:CL_4047022 ObjectIntersectionOf(obo:CL_0000134 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0001962)))
SubClassOf(obo:CL_4047022 obo:CL_0000134)

# Class: obo:CL_4047032 (secretory pericyte)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.3389/fncel.2019.00282") obo:IAO_0000115 obo:CL_4047032 "A specialized pericyte located within the basement membrane of a blood capillary. This cell is characterized by its ability to produce and release a variety of bioactive molecules, collectively known as the pericyte secretome, including cytokines and regulators of angiogenesis.")
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