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update safer reading materials
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peterhcharlton committed Jun 17, 2024
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4 changes: 2 additions & 2 deletions safer_projects/introduction.md
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### The Screening Process

The three main steps of the screening process which I?ll refer to are:
The three main steps of the screening process which I'll refer to are:

- **ECGs recorded at home:** Firstly, participants are sent a handheld device which takes 30-second ECG recordings between two thumbs. Participants are asked to record an ECG 4 times per day, for 3 weeks, producing approximately 84 ECGs per participant.
- **Automated analysis:** Secondly, the ECG recordings are automatically analysed to identify any that may contain AF.
- **Clinical review:** Thirdly, those ECGs which may contain AF are sent for clinical review to make a final diagnosis. Any participants diagnosed with AF then discuss possible anticoagulation with their GP.

## Previous work

An overview of the work I have been involved in so far is provided [here](https://peterhcharlton.github.io/project/safer-wearables/), including publications arising from previous student projects (under the 'Publications' heading lower on the page). A more comprehensive list of publications arising from SAFER is provided [here](https://www.safer.phpc.cam.ac.uk/trial-news/outputs/publications/).
An overview of the work I have been involved in so far is provided [here](https://peterhcharlton.github.io/project/screening-af/), including publications arising from previous student projects (under the 'Publications' heading lower on the page). A more comprehensive list of publications arising from SAFER is provided [here](https://www.safer.phpc.cam.ac.uk/trial-news/outputs/publications/).

## Project Guidelines

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21 changes: 16 additions & 5 deletions tools/reading/af_screening.md
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## Atrial Fibrillation

- [2020 AF Guidelines](https://doi.org/10.1093/eurheartj/ehaa612): includes the 'diagnostic criteria for atrial fibrillation' in Section 3.2.
- [2020 ESC Guidelines](https://doi.org/10.1093/eurheartj/ehaa612): includes the 'diagnostic criteria for atrial fibrillation' in Section 3.2.
- [2021 NICE Guideline](https://www.nice.org.uk/guidance/ng196): includes the [recommendation](https://www.nice.org.uk/guidance/ng196/chapter/Rationale-and-impact#detection-and-diagnosis-2) that '12?lead ECG should be used as the test to confirm atrial fibrillation, to prevent the use of less accurate ECG devices, such as mobile and lead?I ECG devices'.
- [Responsible for a fivefold increase in stroke risk](https://doi.org/0.1161/01.str.22.8.983)

## Screening Studies
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- [SAFER Trial registration](https://www.isrctn.com/ISRCTN72104369)

Protocols:
- [SAFER Trial Pilot Study](https://doi.org/10.1136/bmjopen-2022-065066)
- [SAFER Trial Pilot](https://doi.org/10.1136/bmjopen-2022-065066)
- [SAFER Trial](https://doi.org/10.1136/bmjopen-2023-082047)

Papers:
- [Feasibility Study Results](https://doi.org/10.1093/europace/euae056)
- [Embedding qualitative research in trials](https://doi.org/10.1186/s13063-022-06308-7)
- [Why do people take part in atrial fibrillation screening?](https://doi.org/10.1136/bmjopen-2021-051703)

Engineering Analyses:
- [Algorithm tags and number of reviewers](https://doi.org/10.3390/ecsa-7-08195): initial results
- [Prioritising ECGs for manual review](https://doi.org/10.1109/EMBC48229.2022.9871092)
- [Characterising RR-intervals](https://doi.org/10.22489/CinC.2023.270)

### LOOP Study

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### Apple Heart Study

Study Design:
- [Publication](https://doi.org/10.1016/j.ahj.2018.09.002)
- [Study Design](https://doi.org/10.1016/j.ahj.2018.09.002)
- [Results](https://doi.org/10.1056/NEJMoa1901183)

### FitBit Heart Study

- [Results](https://doi.org/10.1161/CIRCULATIONAHA.122.060291)

## Devices

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### Reviews of screening for AF
- [Population-based screening for atrial fibrillation](https://doi.org/10.1161/CIRCRESAHA.120.316341) - see Table 4 for a list of ongoing studies.
- [Screening for atrial fibrillation: A call for evidence](https://doi.org/10.1093/eurheartj/ehz834)
- [Screening for atrial fibrillation](https://doi.org/10.1161/CIRCULATIONAHA.116.026693)
- [Screening for atrial fibrillation](https://doi.org/10.1161/CIRCULATIONAHA.116.026693)

### Interpreting single-lead ECGs for AF diagnosis
- [Data from the VITAL-AF Trial](https://doi.org/10.1016/j.ahj.2023.07.003)

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