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Quality Control of Genotypes
Hao Cheng edited this page May 27, 2021
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1 revision
Simple quality control is available for genotypes. In get_genotypes
function, when quality_control
=true, minor allele frequency MAF
threshold, defaulting to 0.01, is used, and fixed loci are removed. In addition, missing genotypes will be replaced by column means if they are denoted as 9
. Users can also impute missing genotypes before the analysis.
using JWAS,JWAS.Datasets
genofile = dataset("genotypes.csv")
genotypes = get_genotypes(genofile, separator=',', quality_control=true, MAF=0.05);
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