Merge pull request #87 from steno-aarhus/new-proposal-bmiprs

Project proposal: bmiprs

data-raw/projects/proposals/bmiprs.yaml

@@ -0,0 +1,20 @@
+submitted_on: '2024-08-29'
+full_name: Nuno Nogueira
+github_username: nunonog
+job_position: Postdoc researcher
+phd_supervisor: ''
+affiliation: Aarhus University
+project_title: 'BMIhom: Exploring Childhood PRS'
+project_description: The proposed project aims to investigate the impact of deviations
+  from genetically-determined body mass index (BMI) homeostasis on premature mortality,
+  by leveraging large-scale population studies.This project involves utilizing childhood
+  Polygenic Risk Scores (PRS) as a proxy for genetic homeostatic BMI. Given that secular
+  changes in the environment promoting weight gain have likely influenced adult BMI
+  PRS, the childhood PRS offers a more stable and unbiased estimate of an individual’s
+  genetic predisposition to obesity. This will allow us to assess the long-term health
+  risks associated with deviations from genetically-determined BMI across the lifespan.
+  The findings from this research could lead to the development of personalized health
+  interventions, helping to identify those at higher risk of mortality due to weight-related
+  factors.
+agree_to_conditions: 'Yes'
+