April 2023 release

Added new patterns and terms for diagnostic and therapeutic procedure by site

diagnostic procedure by site (MAXO:0000988)
diagnostic procedure of cardiovascular system (MAXO:0000493)
diagnostic procedure of digestive system (MAXO:0001396)
diagnostic procedure of circulatory system (MAXO:0001398)
diagnostic procedure of excretory system (MAXO:0001399)
diagnostic procedure of exocrine system (MAXO:0001400)
diagnostic procedure of genitourinary system (MAXO:0001401)
diagnostic procedure of hematopoietic system (MAXO:0001402)
diagnostic procedure of integumental system (MAXO:0001403)
diagnostic procedure of skin (MAXO:0001404)
diagnostic procedure of musculoskeletal system (MAXO:0001405)
diagnostic procedure of nervous system (MAXO:0001406)
diagnostic procedure of reproductive system (MAXO:0001407)
diagnostic procedure of respiratory system (MAXO:0001408)
diagnostic procedure of visual system (MAXO:0001444)
diagnostic procedure of auditory system (MAXO:0001445)
diagnostic procedure of immune system (MAXO:0001446)
diagnostic procedure of body substance (MAXO:0001447)
diagnostic procedure of amniotic fluid (MAXO:0001448)
diagnostic procedure of blood clot (MAXO:0001449)
diagnostic procedure of excreted substance (MAXO:0001450)
diagnostic procedure of feces (MAXO:0001451)
diagnostic procedure of urine (MAXO:0001452)
diagnostic procedure of interstitial fluid (MAXO:0001453)
diagnostic procedure of ocular refractive media (MAXO:0001454)
diagnostic procedure of aqueous humor of eyeball (MAXO:0001455)
diagnostic procedure of vitreous humor (MAXO:0001456)
diagnostic procedure of pus (MAXO:0001457)
diagnostic procedure of reproductive gland secretion (MAXO:0001458)
diagnostic procedure of female reproductive gland secretion (MAXO:0001459)
diagnostic procedure of male reproductive gland secretion (MAXO:0001460)
diagnostic procedure of respiratory system fluid/secretion (MAXO:0001461)
diagnostic procedure of sputum (MAXO:0001462)
diagnostic procedure of exocrine gland secretion (MAXO:0001463)
diagnostic procedure of bile (MAXO:0001464)
diagnostic procedure of gastric juice (MAXO:0001465)
diagnostic procedure of semen (MAXO:0001466)
diagnostic procedure of organ (MAXO:0001467)
therapeutic procedure by site (MAXO:0000034)
therapeutic procedure of visual system (MAXO:0001397)
therapeutic procedure of digestive system (MAXO:0001409)
therapeutic procedure of cardiovascular system (MAXO:0001410)
therapeutic procedure of circulatory system (MAXO:0001411)
therapeutic procedure of excretory system (MAXO:0001412)
therapeutic procedure of exocrine system (MAXO:0001413)
therapeutic procedure of genitourinary system (MAXO:0001414)
therapeutic procedure of hematopoietic system (MAXO:0001415)
therapeutic procedure of integumental system (MAXO:0001416)
therapeutic procedure of skin of body (MAXO:0001417)
therapeutic procedure of musculoskeletal system (MAXO:0001418)
therapeutic procedure of nervous system (MAXO:0001419)
therapeutic procedure of reproductive system (MAXO:0001420)
therapeutic procedure of respiratory system (MAXO:0001421)
therapeutic procedure of vestibulo-auditory system (MAXO:0001422)
therapeutic procedure of immune system (MAXO:0001423)
therapeutic procedure of organism substance (MAXO:0001424)
therapeutic procedure of amniotic fluid (MAXO:0001425)
therapeutic procedure of blood clot (MAXO:0001426)
therapeutic procedure of excreta (MAXO:0001427)
therapeutic procedure of feces (MAXO:0001428)
therapeutic procedure of urine (MAXO:0001429)
therapeutic procedure of interstitial fluid (MAXO:0001430)
therapeutic procedure of ocular refractive media (MAXO:0001431)
therapeutic procedure of aqueous humor of eyeball (MAXO:0001432)
therapeutic procedure of vitreous humor (MAXO:0001433)
therapeutic procedure of pus (MAXO:0001434)
therapeutic procedure of reproductive gland secretion (MAXO:0001435)
therapeutic procedure of female reproductive gland secretion (MAXO:0001436)
therapeutic procedure of male reproductive gland secretion (MAXO:0001437)
therapeutic procedure of respiratory system fluid/secretion (MAXO:0001438)
therapeutic procedure of sputum (MAXO:0001439)
therapeutic procedure of secretion of exocrine gland (MAXO:0001440)
therapeutic procedure of bile (MAXO:0001441)
therapeutic procedure of gastric juice (MAXO:0001442)
therapeutic procedure of organ (MAXO:0001443)
New Maxolyzer terms

MAXO:0035121 | electrooculogram procedure
MAXO:0035120 | cardiac auscultation
MAXO:0035119 | duplex ultrasound with color flow imaging
MAXO:0035118 | cardiac catheterization
MAXO:0035115 | diffusion weighted cerebral MRI
MAXO:0035114 | immune cell function assay
MAXO:0035113 | platelet transmission electron microscopy
MAXO:0035054 | protein glycosylation assay
MAXO:0035110 | gustatory testing
MAXO:0035109 | immune complex assay
MAXO:0035108 | sweat electrolyte test
MAXO:0035106 | paracentesis
MAXO:0035105 | salivary cortisol test
MAXO:0035104 | motor evoked potential evaluation
MAXO:0035103 | refraction test
MAXO:0035102 | water deprivation test
MAXO:0035101 | phrenic nerve stimulation test
MAXO:0035099 | electroretinogram procedure
MAXO:0035096 | breath hydrogen test
MAXO:0035094 | platelet aggregation assay
MAXO:0035093 | erythrocyte sedimentation rate measurement
MAXO:0035092 | fractional excretion assessment
MAXO:0035091 | electromyography procedure
MAXO:0035084 | fructose tolerance test
MAXO:0035083 | CT urogram
MAXO:0035080 | apoptosis assay
MAXO:0035079 | neonatologist evaluation
MAXO:0035078 | pulmonary function testing
MAXO:0035077 | functional T cell assessment
MAXO:0035076 | complement assay
MAXO:0035068 | natural killer cell function test
MAXO:0035067 | perchlorate discharge test
MAXO:0035066 | somatosensory evoked potential assessment
MAXO:0035065 | dentist evaluation
MAXO:0035064 | electron microscopic study
MAXO:0035063 | jerk-locked averaging
MAXO:0035058 | hormone measurement
MAXO:0035062 | urine hormone measurement
MAXO:0035059 | nerve conduction study
MAXO:0035057 | reproductive endocrinologist assessment
MAXO:0035055 | flow cytometry procedure
MAXO:0035040 | abdominal paracentesis
MAXO:0035025 | in vitro DNA repair study
MAXO:0035028 | L-selectin shedding study
MAXO:0035036 | blood culture procedure
MAXO:0035017 | hair microscopy
MAXO:0035005 | circulating hormone measurement
MAXO:0035027 | blood gas assessment in umbilical cord blood
MAXO:0035011 | enzyme activity assessment
MAXO:0035026 | circulating immunoglobulin measurement
MAXO:0035029 | cerebrospinal fluid metabolite measurement
MAXO:0035019 | erythrocyte enzyme activity assessment
MAXO:0035018 | leukocyte enzyme activity assessment
MAXO:0035020 | tissue enzyme activity assessment
MAXO:0035047 | stool metabolite measurement
MAXO:0035031 | stool xenobiotic measurement
MAXO:0035023 | tissue metabolite measurement
MAXO:0035032 | gastric fluid xenobiotic measurement
MAXO:0035033 | hair xenobiotic measurement
MAXO:0035117 | cardiac exercise stress test
MAXO:0035090 | hepatobiliary iminodiacetic acid scan
MAXO:0035097 | visual evoked potential procedure
MAXO:0035075 | sperm analysis
MAXO:0035069 | dysmorphology assessment
MAXO:0035107 biopsy of carotid artery
MAXO:0035095 venography procedure
MAXO:0035089 nasal endoscopy
MAXO:0035071 reactive oxygen species measurement
MAXO:0035061 pelvic CT

Added
body measurement (MAXO:0001011)
body shape assessment (MAXO:0000997)
head morphology assessment (MAXO:0000999)
facial morphology assessment (MAXO:0000998)
facial morphology assessment by type (MAXO:0001028)
3D facial analysis (MAXO:0001090)
waist measurement (MAXO:0001012)
hip measurement (MAXO:0001013)
waist to hip ratio calculation (MAXO:0001024)
therapy
occupational therapy
feeding therapy
applied behavioral analysis therapy

March 09 2023 release

New terms added

MAXO:0035001 hand radiograph procedure
MAXO:0035002 intraoral radiograph procedure.
MAXO:0035006 foot radiograph procedure
MAXO:0035038 contrast angiography procedure
MAXO:0035035 lymphography
MAXO:0035049 endoscopic retrograde cholangiopancreatography
MAXO:0035008 shoulder radiograph
MAXO:0035074 ankle radiograph
MAXO:0035082 barium swallow radiograph procedure
MAXO:0035085 cervical spine radiograph
MAXO:0035003 fluorescein angiography
MAXO:0001321 nuclear medicine imaging procedure
MAXO:0000007 radiograph imaging with contrast dye
MAXO:0001336 neurotransmitter agent therapy
MAXO:0001337 GABA agonist agent therapy
MAXO:0001338 GABAA receptor agonist therapy
MAXO:0001339 GABAB receptor agonist therapy
MAXO:0001320 GABA antagonist therapy
MAXO:0001340 GABAA receptor antagonist therapy
MAXO:0001322 GABA modulator therapy
MAXO:0001323 cholinergic agent therapy
MAXO:0001324 cholinergic agonist therapy
MAXO:0001325 muscarinic agonist therapy
MAXO:0001326 nicotinic acetylcholine receptor agonist therapy
MAXO:0001327 cholinergic antagonist therapy
MAXO:0001328 muscarinic antagonist therapy
MAXO:0001329 nicotinic antagonist therapy
MAXO:0001330 parasympatholytic therapy
MAXO:0001331 dopaminergic modifying agent therapy
MAXO:0001332 dopamine agonist therapy
MAXO:0001333 dopamine receptor D1 agonist therapy
MAXO:0001334 dopamine uptake inhibitor therapy
MAXO:0001335 dopaminergic antagonist agent therapy
MAXO:0000968 fundoscopy
MAXO:0000967 ophthalmic diagnostic procedure
MAXO:0000969 optical coherence tomography
MAXO:0000974 tonometry
MAXO:0000971 vision assessment
MAXO:0000972 eye movement measurement
MAXO:0000970 gonioscopy
MAXO:0000962 glaucoma filtration surgery
MAXO:0000024 surgical procedure on the eye
MAXO:0000961 non-penetrating glaucoma surgery
MAXO:0000958 deep sclerectomy
MAXO:0001082 trabeculectomy
MAXO:0000960 viscocanalostomy
MAXO:0000959 canaloplasty
MAXO:00001341 sclerectomy
MAXO:0035087 biopsy of peripheral nerve
MAXO:0035098 biopsy of artery
MAXO:0001342 colostomy
MAXO:0001343 cystostomy procedure
MAXO:0001344 enterostomy
MAXO:0001345 ureterostomy
MAXO:0000504 tracheotomy
MAXO:0001346 gastrostomy
MAXO:0001347 duodenostomy
MAXO:0001348 ileostomy
MAXO:0001349 jejunostomy
MAXO:0001350 nephrostomy
MAXO:0000979 laparoscopic-assisted anorectoplasty
MAXO:0000977 pull-through procedure
MAXO:0000965 ostomy surgical procedure
MAXO:0001352 surgical repair of anorectum
MAXO:0001353 surgical repair of large intestine
MAXO:0001354 surgical repair of intestine
MAXO:0001355 surgical repair of small intestine
MAXO:0000966 posterior sagittal anorectoplasty
MAXO:0000026 diathermy
MAXO:0000027 microwave diathermy
MAXO:0000030 short wave diathermy
MAXO:0000028 ultrasound therapy
MAXO_0000029 cell measurement
MAXO_0000033 cell morphology assessment
MAXO_0001006 hematopoietic cell count
MAXO_0000543 eosinophil count
MAXO_0000544 granulocyte count
MAXO_0000545 basophil count
MAXO_0000546 lymphocyte count
MAXO_0000825 reticulocyte count
MAXO_0000830 erythrocyte morphology measurement
MAXO_0001006 hematopoietic cell count
MAXO_0001007 erythrocyte count
MAXO_0001008 platelet count
MAXO_0001009 neutrophil count
MAXO_0001010 leukocyte count
MAXO_0001356 hematopoietic cell morphology measurement
MAXO_0001357 lymphocyte morphology measurement
MAXO_0001358 reticulocyte morphology measurement
MAXO_0001359 leukocyte morphology measurement
MAXO_0001360 granulocyte morphology measurement
MAXO_0001361 basophil morphology measurement
MAXO_0001362 neutrophil morphology measurement
MAXO_0001363 platelet morphology measurement
MAXO_0001364 sperm morphology measurement
MAXO_0001365 T cell morphology measurement
MAXO_0001366 B cell morphology measurement
MAXO_0001367 sperm count
MAXO_0001368 helper T cell count
MAXO_0001369 T cell count
MAXO_0001369 T cell count
MAXO_0001370 B cell count
MAXO_0001371 natural killer cell count
MAXO_0001372 burr cell count
MAXO_0001373 plasma cell count
MAXO_0001374 dendritic cell count
MAXO_0001375 regulatory T cell count
MAXO_0001376 natural killer cell morphology measurement
MAXO_0001377 echynocyte morphology measurement
MAXO_0001378 Langerhans cell morphology measurement
MAXO_0001379 mast cell morphology measurement
MAXO_0001380 Schwann cell morphology measurement
MAXO_0001381 myeloid cell morphology measurement
MAXO_0001382 germ cell morphology measurement
MAXO_0001383 glial cell morphology measurement
MAXO_0001384 kidney glomerular endothelial cell morphology measurement
MAXO_0001385 oocyte morphology measurement
MAXO_0001386 myeloid leukocyte morphology measurement
MAXO_0001387 bone marrow cell morphology measurement
MAXO_0001388 megakaryocyte morphology measurement

Other updates

• added new cell morphology pattern and terms
• added new cell count pattern and terms
• Added new ostomy pattern and terms
• added synonym biopsy of oral cavity to biopsy of mouth
• replace tranquilizing agent therapy with mood and behavior modifying agent therapy
• removed biopsy of muscle organ and replaced with biopsy of muscle tissue
• Updated biopsy labels and definitions to make not sound as awkward.
• removed total body radiography and total body MRI from pattern to remove axioms because implications are not what was intended

February 2023

Major update

• There was a major update to the maxo-import system
• Updates to MAxO reports and QC
• update to seed.txt
• Update ODK 1.4

Additional updates

• Fixed stray class that was causing errors (it was from an unimplemented DOSDP pattern)
• Fixed many issues giving rise to duplicate synonyms--largely through issues with the import label and the pattern used.
• Fixed a number of labels that were duplicated. Largely in the pharmacotherapy branch where the DOSDP pattern was updated, but not all the terms were fixed.
• Added definitions to ~ 10 terms (classes and data properties) that were missing
• Fixed issue with 'whole organ transplantation' and 'partial organ implantation' terms
• Fixed a handful of incorrect ORCID IDs in the organ transplantation pattern
• Updated clinical imaging to be in the diagnostic branch
• Added terms to MRI pattern
• Updated MRI pattern to handle extra synonyms and additional naming procedures
• Update DOSDP descriptions
• added health management and support terms diabetes education, and early intervention support
• added reconstruction by location pattern and repair by location pattern
• updated biomarker analysis hierarchy
• added avoidance of immunosuppressants
• added new terms for patient health management, diabetes education

December 2022 release #2

This is the second release focusing on fixes to MAxO. More new terms will be available after the next release.

Fixes

• Update pharmacotherapy logical definition. Because it was included in the pharmacotherapy pattern, the logical definition caused a circular reference which caused the term to act as a root of the ontology.
• updated minor typos in ct_by_location pattern
• changed all location patterns (13 total) to narrow uses of UBERON from owl:thing to anatomy entity.
• updated the hierarchy of clinical laboratory procedure and disease screening.

Other

• Change the id range from Aaron Zhang to Peter for maxylizer annotation project.

December 2022 release

This release has several fixes to the ontology.

Fixes

• First, somehow 'inheres_in' was somehow made SubClassOf radioactive. This was an entirely accidental relationship and it was (finally) removed.
• Avoid patterns updates: The logical definitions needed to be broken down to keep from 'avoid all food' when 'avoid some food' was the intended outcome.
• Third, the biopsy and collection of specimen with swab patterns were updated. Previously, we erroneously changed the hierarchy of these terms. To correct this and to narrow the scope of the ontology, the terms are 'clinical biopsy' and 'clinical swab collection'
• Fourth, more technically, we severely limited the HP imports because they were causing duplicates and other import issues.

November 2022 Release #2

Accidental axiom was created where inheres_in was a child of radioactive. This release fixes that assertion.

November 2022 Release

What's Changed

• Made several Nutrtion medical action updates:

• • fix supplementation branch
• • add fat soluble supplementation terms
• • add selenium supplementation and selenium avoidance

• add oxygen supplementation

• Split transplantation pattern into 2 patterns where one is part of an organ and one is whole organ transplantation.

• Update README

Full Changelog: v2022-08-31...v2022-11-14

August 2022 release

Updated maxo.Makefile and also started ROBOT templates to add terms. Created surgical_repair_by_location pattern.

Add new INCLUDE terms

• MAXO:0025001 cardiac surgery
• MAXO:0025002 heart repair
• MAXO:0025003 vision treatment
• MAXO:0025004 glasses usage
• MAXO:0025005 nasolacrimal duct surgery
• MAXO:0025006 strabismus surgery

Other terms added

• MAXO:0009094 Janus kinase inhibitor therapy
• MAXO:0009097 GABA transaminase inhibitor therapy

Also, added synonym to tumorectomy, cancer surgery.

June 2022 release

Added many new terms and fixed some typos.

• chemical measurement and vitamin measurement patterns added

• stereotactic radiation therapy

• stereotactic radiosurgery

• stereotactic radiosurgery using proton beam therapy

• stereotactic radiosurgery using Gamma Knife

• stereotactic radiosurgery using Linear Accelerator

• stereotactic body radiation therapy

• cosmetic plastic surgery

• abdominoplasty

• breast augmentation surgery

• reconstructive plastic surgery

• cheiloplasty

• mammoplasty

• palatorrhaphy

• reconstructive burn surgery

• surgical repair

• arthroplasty

• hip arthroplasty

• knee arthroplasty

• pelvic radiograph procedure'

• intravenous pyelogram'

• SPECT

• nuclear medicine procedure

• skull radiograph

• zinc therapy

• Remove logical axioms from mediastinoscopy and thoracoscopy because they were 'spaces' and not entities.

April/May 2022 release

Add new terms

• cochlear device implantation
• hearing therapy
• cochlear implant
• introduction procedure
• electrode implantation
• auditory brainstem implantation
• hearing aid usage
• child audiologic habilitation
• add pacemakers
• coronary stent implantation
• infusion pump implantation
• infusion pump therapy
• insulin infusion pump therapy
• infusion
• cataract removal with IOL insertion
• total hip replacement
• total knee replacement
• myringotomy and insertion of tympanic ventilation tube
• implantation of joint prosthesis
• examination by medical specialty and examination by allied health professional branches

Add definition

• defintion to auditory rehabilitation
• update enucleation definition, children terms